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class="fa fa-fw"></i><a href="../2898/paper-2-questions-topic-5-evolution.html">Paper 2 questions Topic 5 Evolution</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../462/01-cell-biology.html">01 Cell biology</a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../486/introduction-to-cells-11.html">Introduction to cells 1.1</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../606/ultrastructure-of-cells-12-.html">Ultrastructure of cells 1.2 </a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../607/membrane-structure-13-.html">Membrane structure 1.3 </a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../575/membrane-transport-14-.html">Membrane transport 1.4 </a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../608/the-origin-of-cells-15.html">The origin of cells 1.5</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../609/cell-division-16.html">Cell division 1.6</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../463/02-molecular-biology.html">02 Molecular biology</a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../577/molecules-to-metabolism-21.html">Molecules to metabolism 2.1</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../578/water-22.html">Water 2.2</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../600/carbohydrates-lipids-23.html">Carbohydrates & Lipids 2.3</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../601/proteins-24.html">Proteins 2.4</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../585/enzymes-25.html">Enzymes 2.5</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../602/structure-of-dna-and-rna-26.html">Structure of DNA and RNA 2.6</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../603/dna-replication-transcription-translation-27.html">DNA Replication, transcription, translation 2.7</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../604/respiration-28.html">Respiration 2.8</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../605/photosynthesis-29.html">Photosynthesis 2.9</a></label></li></ul></li><li class="expanded parent selected"><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="03-genetics-sl.html">03 Genetics SL</a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../790/genes-31-.html">Genes 3.1 </a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../791/chromosomes-32.html">Chromosomes 3.2</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../792/meiosis-33.html">Meiosis 3.3</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../793/inheritance-34.html">Inheritance 3.4</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../794/genetic-modification-35.html">Genetic Modification 3.5</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../466/04-ecology-.html">04 Ecology </a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../795/species-and-communities-41-.html">Species and communities 4.1 </a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../796/energy-flow-42.html">Energy flow 4.2</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../797/carbon-cycle-43-.html">Carbon Cycle 4.3 </a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../798/climate-change-44.html">Climate change 4.4</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../467/05-evolution-.html">05 Evolution </a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../799/evidence-for-evolution-51-.html">Evidence for evolution 5.1 </a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../800/natural-selection-52.html">Natural selection 5.2</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../801/classification-of-biodiversity-53-.html">Classification of biodiversity 5.3 </a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../802/cladistics-54.html">Cladistics 5.4</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../468/06-human-physiology.html">06 Human physiology</a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../579/digestion-absorption-61.html">Digestion & absorption 6.1</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../580/blood-system-62.html">Blood system 6.2</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../591/defence-against-disease-63.html">Defence against disease 6.3</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../592/gas-exchange-64.html">Gas exchange 6.4</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../593/neurones-and-synapses-65.html">Neurones and synapses 6.5</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../594/hormones-and-reproduction-66.html">Hormones and reproduction 6.6</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../469/07-nucleic-acids-ahl.html">07 Nucleic acids AHL</a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1160/nucleic-acids-71-hl.html">Nucleic acids 7.1 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1157/transcription-72-hl.html">Transcription 7.2 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1158/translation-73-hl.html">Translation 7.3 HL</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../470/08-metabolism-ahl.html">08 Metabolism AHL</a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1195/metabolism-81-hl.html">Metabolism 8.1 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1196/cell-respiration-82-hl.html">Cell respiration 8.2 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1197/photosynthesis-83-hl.html">Photosynthesis 8.3 HL</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../471/09-plant-biology-ahl.html">09 Plant biology AHL</a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1251/transport-in-xylem-91-hl.html">Transport in xylem 9.1 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1252/transport-in-phloem-92-hl.html">Transport in phloem 9.2 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1253/growth-in-plants-93-hl.html">Growth in plants 9.3 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1254/reproduction-in-plants-94-hl.html">Reproduction in plants 9.4 HL</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../472/10-genetics-ahl.html">10 Genetics AHL</a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1341/meiosis-101-hl.html">Meiosis 10.1 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1342/inheritance-102-hl.html">Inheritance 10.2 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1343/gene-pools-and-speciation-103-hl.html">Gene pools and speciation 10.3 HL</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><a class="expander" href="#" style="font-size: .9em"><i class="fa fa-fw fa-caret-right"></i></a><a href="../473/11-animal-physiology-ahl.html">11 Animal physiology AHL</a></label><ul class="side-nav level-1"><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../2063/antibody-production-vaccination-111-hl.html">Antibody production & vaccination 11.1 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1345/movement-112-hl.html">Movement 11.2 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1346/kidney-and-osmoregulation-113-hl.html">Kidney and osmoregulation 11.3 HL</a></label></li><li class=""><label style="padding-left: 14px"><i class="fa fa-fw"></i><a href="../1347/sexual-reproduction-114-hl.html">Sexual reproduction 11.4 HL</a></label></li></ul></li><li class=""><label style="padding-left: 0px"><i class="fa fa-fw"></i><a href="../2824/option-a-neurobiology.html">Option A - Neurobiology</a></label></li><li class=""><label style="padding-left: 0px"><i class="fa fa-fw"></i><a href="../2852/option-b-biotechnology.html">Option B - Biotechnology</a></label></li><li class=""><label style="padding-left: 0px"><i class="fa fa-fw"></i><a href="../2853/option-c-ecology.html">Option C - Ecology</a></label></li><li class=""><label style="padding-left: 0px"><i class="fa fa-fw"></i><a href="../2854/option-d-human-physiology.html">Option D Human physiology</a></label></li></ul></div> <div class="hidden-xs hidden-sm"> <button class="btn btn-default btn-block text-xs-center" data-toggle="modal" data-target="#modal-feedback" style="margin-bottom: 10px"><i class="fa fa-send"></i> Feedback</button> </div> </div> <div class="col-md-9" id="main-column"> <h1 class="page_title"> 03 Genetics SL <a href="#" class="mark-page-favorite pull-right" data-pid="465" title="Mark as favorite" onclick="return false;"><i class="fa fa-star-o"></i></a> </h1> <ol class="breadcrumb"> <li><a href="../../../biology.html"><i class="fa fa-home"></i> Home</a><i class="fa fa-fw fa-chevron-right divider"></i></li><li><span class="gray">03 Genetics SL</span></li> </ol> <article id="main-article"> <h3><span class="mw-headline" id="Topic_4:_Ecology"></span></h3> <h3><span class="mw-headline" id="Topic_3:_Genetics"><img alt="" height="168" src="../../images/03_genetics/meiosis_painting.jpg" style="float: right;" width="168">Topic 3: <a href="https://en.wikibooks.org/wiki/IB_Biology/Genetics" title="IB Biology/Genetics">Genetics</a></span></h3> <p>This is an introduction to the SL genetics topic. It lists understandings and skills expected for Topic 3 including genes, chromosomes, meiosis, the theoretical genetics of inheritance, GMOs and biotechnology. Helpful for revision.<br> Detailed revision notes, activities and questions can be found for each of the sub-topic pages:</p> <ul> <li>3.1 Genes</li> <li>3.2 Chromosomes</li> <li>3.3 Meiosis</li> <li>3.4 Inheritance</li> <li>3.5 Genetic modification and biotechnology <hr class="hidden-separator"></li> </ul> <div class="blueBg"> <h3>3.1 Genes</h3> <ul> <li>Definition of a gene is, "a heritable factor that consists of a length of DNA and influences a specific characteristic."</li> <li>A gene locus is, "the specific position of a gene on a chromosome."</li> <li>Alleles are, "The various specific forms of a gene which differ from each other by one or only a few bases".</li> <li>New alleles are formed by mutation.</li> <li>A genome is, "the whole of the genetic information of an organism."</li> <li>The entire base sequence of human genes was sequenced in the Human Genome Project.</li> <li>The Genbank® database can be used to search for DNA base sequences.</li> </ul> <div class="box"> <p><strong>Skills ( can you ... ) </strong></p> <ul> <li class="liWithoutP">Explain the causes of sickle cell anemia, including a base substitution mutation, subsequent change to the mRNA transcribed from it and a change to the sequence of amino acids in a polypeptide of hemoglobin.</li> <li class="liWithoutP">Recall of one specific base substitution that causes glutamic acid to be substituted by valine as the sixth amino acid in the hemoglobin polypeptide is required. (Deletions, insertions and frame shift mutations are <strong>not</strong> needed.)</li> <li class="liWithoutP">Compare the number of genes in humans with other species.<br> At least one plant and one bacterium should be included in the comparison and at least one species with more genes and one with fewer genes than a human.<br> (note: "genome size" is total amount of DNA, not the number of genes in a species)</li> <li class="liWithoutP">Use of a database to determine differences in the base sequence of a gene in two species. <a href="http://www.ncbi.nlm.nih.gov/genbank/">Look up "GENBANK"</a></li> </ul> </div> <ul> </ul> </div> <div class="blueBg"> <h3><img alt="" src="../../images/03_genetics/chromatin-to-chromosome.jpg" style="float: right; width: 250px; height: 104px;">3.2 Chromosomes</h3> <ul> <li class="liWithoutP">Prokaryotes have one single circular DNA molecules as a chromosome.</li> <li class="liWithoutP">Some prokaryotes also have plasmids but eukaryotes don't.</li> <li class="liWithoutP">Eukaryote chromosomes are linear DNA molecules associated with histone proteins.</li> <li class="liWithoutP">In a eukaryote species there are a characteristic number of different chromosomes each carrying different genes.</li> <li class="liWithoutP">Pairs of chromosomes with the same sequence of genes (not necessarily the same alleles) are "Homologous chromosomes"</li> <li class="liWithoutP">Diploid nuclei have pairs of homologous chromosomes.</li> <li class="liWithoutP">Haploid nuclei have one chromosome of each pair.</li> <li class="liWithoutP">Sister chromatids are the two DNA molecules formed by DNA replication before cell division</li> <li class="liWithoutP">two separate chromosomes are formed at the splitting of the centromere at the start of anaphase.</li> <li class="liWithoutP">A karyogram (a chart) shows the chromosomes of an organism in homologous pairs of decreasing length. (Karyotype is the number and type of chromosomes present in the nucleus)</li> <li class="liWithoutP">Sex chromosomes determine the gender of an individual and autosomes are chromosomes that do not determine sex.</li> </ul> <div class="box"> <p><strong>Skills (can you ....)</strong></p> <ul> <li>Understand Cairns’ technique for measuring the length of DNA molecules by autoradiography.</li> <li>Compare genome size in T2 phage, <em>Escherichia coli</em>, <em>Drosophila melanogaster</em>, <em>Homo sapiens</em> and <em>Paris japonica. (</em>selected for points of interest.Genome size comparative activity</li> <li>Use karyograms to compare diploid chromosome numbers of <em>Homo sapiens</em>, <em>Pan troglodytes</em>, <em>Canis familiaris</em>, <em>Oryza sativa</em>, <em>Parascaris equorum.</em></li> <li>Use karyograms to deduce sex and diagnose Down syndrome in humans.</li> <li>Use of databases to identify the locus of a human gene and its polypeptide product</li> </ul> </div> </div> <div class="blueBg"> <h3>3<img alt="" src="../../images/03_genetics/meiosis_painting.jpg" style="float: right; width: 200px; height: 200px;" title="Image: Kingsway school, CC">.3 Meiosis</h3> <ul> <li>Meiosis produces four haploid nuclei from one diploid nucleus.</li> <li>Haploid nuclei allow a life cycle with fusion of gametes.</li> <li>DNA is replicated before meiosis so that all chromosomes at start of meiosis are 'double stranded' with two sister chromatids.</li> <li>The early stages of meiosis involve pairing of homologous chromosomes and crossing over followed by condensation.</li> <li>Random orientation of pairs of homologous chromosomes.</li> <li>Separation of pairs of homologous chromosomes in the first division of meiosis halves the chromosome number.</li> <li>Genetic variation is the result of crossing over and random orientation.</li> <li>Different parents providing gametes promotes genetic variation.</li> </ul> <div class="box"> <p><strong>Skills ( can you ...)</strong></p> <ul> <li class="liWithoutP">Describe how non-disjunction can cause Downs syndrome and other chromosome abnormalities.</li> <li class="liWithoutP">Remember studies showing age of parents influences chances of non-disjunction.</li> <li class="liWithoutP">Describe methods used to obtain cells for karyotype analysis e.g. chorionic villus sampling and amniocentesis and the associated risks.</li> <li class="liWithoutP">Draw diagrams to show the stages of meiosis (possibly using prepared slides), and resulting in the formation of four haploid cells. (Chiasmata not required)</li> </ul> </div> </div> <div class="blueBg"> <h3 class="liWithoutP"><img alt="" src="../../images/03_genetics/punnet_sqr.jpg" style="float: right; width: 205px; height: 171px;" title="">3.4 Inheritance</h3> <ul> <li class="liWithoutP">Mendel experiments with pea plants showing his rules of inheritance.</li> <li class="liWithoutP">Gametes are haploid so contain only one allele of each gene.</li> <li class="liWithoutP">The two alleles of each gene separate independently during meiosis.</li> <li class="liWithoutP">Fusion of gametes results in diploid zygotes with two alleles of each gene.</li> <li class="liWithoutP">Dominant alleles mask the effects of recessive alleles but co-dominant alleles have joint effects.</li> <li class="liWithoutP">Many genetic diseases in humans are due to recessive, dominant or co-dominant alleles of autosomal genes.</li> <li class="liWithoutP">Some genetic diseases are sex-linked, shown as superscript letters eg. X<sup>h</sup>. The pattern of inheritance is different due to their location on sex chromosomes.</li> <li class="liWithoutP">Many genetic diseases have been identified in humans & most are very rare.</li> <li class="liWithoutP">Radiation and mutagenic chemicals increase the mutation rate and can cause genetic diseases and cancer.</li> </ul> <div class="box"> <p><strong>Skills (can you ....)</strong></p> <ul> <li>Explain the inheritance of ABO blood groups.using I<sup>A</sup>, I<sup>B</sup> or i allele notation.</li> <li>Explain inheritance of red-green colour blindness and hemophilia as examples of sex-linked inheritance.</li> <li>Explain the autosomal inheritance of cystic fibrosis and Huntington’s disease.</li> <li>Construct Punnett grids for monohybrid genetic crosses.</li> <li>Compare predicted and actual outcomes of genetic crosses using real data.</li> <li>Analyse pedigree charts and to deduce the pattern of inheritance of genetic diseases.</li> </ul> </div> </div> <div class="blueBg"> <h3 class="liWithoutP"><img alt="" src="../../images/03_genetics/dna_profiles-1.jpg" style="height: 178px; width: 200px; float: right;" title="Image: CC by Ollie Seibelt on Flickr">3.5 Genetic Modification</h3> <ul> <li>Gel electrophoresis is used for the separation of fragments of DNA (or proteins).</li> <li>PCR (polymerase chain reaction) can be used to make many copies of small amounts of DNA. (called amplification)</li> <li>DNA profiling uses PCR and gel electrophoresis to compare samples of DNA (eg. in paternity disputes)</li> <li>Genetic modification is the transfer of genes from one species to another.</li> <li>Clones are groups of genetically identical organisms, derived from a single original parent cell.</li> <li>Many plant species and some animal species have natural methods of cloning.</li> <li>Animals can be cloned at the embryo stage by breaking up the embryo into more than one group of cells. or by using differentiated cells in adults.</li> <li>The cloned sheep, Dolly can be used as an example of the cloning method of somatic-cell nuclear transfer.</li> </ul> <div class="box"> <p class="liWithoutP"><strong>Skills (can you ....)</strong></p> <ul> <li class="liWithoutP">Use images of DNA profiling to solve paternity disputes and other forensic examples.</li> <li class="liWithoutP">Explain that Gene transfer using plasmids in bacteria makes use of the enzymes; restriction endonucleases and DNA ligase.</li> <li class="liWithoutP">Assess the potential risks and benefits of GMO crops, including data on risks to monarch butterflies of Bt crops.</li> <li class="liWithoutP">Design of an experiment to assess one factor affecting the rooting of stem-cuttings of a plant which easily produces roots in soil.</li> </ul> </div> </div> <hr class="thin"><div class="row"><div class="col-md-12"><br><ul class="resources"><li class="resource-item"><div class="img-container"><img class="thumb thumb-cover" src="../../images/03_genetics/karyotype_activity_male.jpg"></div><div class="media-body"><h4 style="font-size: 19px;"><a class="text-normal" href="../791/chromosomes-32.html">Chromosomes 3.2</a></h4><p class="body">Chromosomes are circular in prokaryotes and linear in eukaryotes. The number of chromosomes is a characteristic of eukaryote species. The structure and shape of the chromosomes in an organism can also give information about the genetic diseases and gender.</p></div></li><li class="resource-item"><div class="img-container"><img class="thumb thumb-cover" src="../../images/03_genetics/gene_proteins.png"></div><div class="media-body"><h4 style="font-size: 19px;"><a class="text-normal" href="../790/genes-31-.html">Genes 3.1 </a></h4><p class="body">Genes provide the instructions to build proteins and more besides. The human genome has been decoded by the human genome project and now biologists can search databases to find the location of specific genes. </p></div></li><li class="resource-item"><div class="img-container"><img class="thumb thumb-cover" src="../../images/03_genetics/gel_electrophoresis_vsmall.png"></div><div class="media-body"><h4 style="font-size: 19px;"><a class="text-normal" href="../794/genetic-modification-35.html">Genetic Modification 3.5</a></h4><p class="body">The ability to find the sequence of the DNA code has provided new tools for biologists to investigate and manipulate DNA. These tools include PCR, gel electrophoresis, DNA profiling, genetic modification. This topic covers these techniques.</p></div></li><li class="resource-item"><div class="img-container"><img class="thumb thumb-cover" src="../../images/03_genetics/green_yellow_fruit.png"></div><div class="media-body"><h4 style="font-size: 19px;"><a class="text-normal" href="../793/inheritance-34.html">Inheritance 3.4</a></h4><p class="body">Theoretical genetics started with Gregor Mendel who established some simple rules of inheritance based on the idea that characteristics or "traits" are inherited independently. The gametes carry a single copy of any gene which becomes a pair of alleles.</p></div></li><li class="resource-item"><div class="img-container"><img class="thumb thumb-cover" src="../../images/03_genetics/meiosis_painting-1.jpg"></div><div class="media-body"><h4 style="font-size: 19px;"><a class="text-normal" href="../792/meiosis-33.html">Meiosis 3.3</a></h4><p class="body">Meiosis is the process which allows sexual reproduction to be possible. It produces four haploid cells which make gametes. In this topic you cover how the chromosomes move during meiosis, crossing over of chromatids and non-disjunction.</p></div></li></ul></div></div> <div id="modal-feedback" class="modal fade" tabindex="-1" role="dialog"> <div class="modal-dialog" role="document"> <div class="modal-content"> <div class="modal-header"> <h4 class="modal-title">Feedback</h4> <button type="button" class="close hidden-xs hidden-sm" data-dismiss="modal" aria-label="Close"> <span aria-hidden="true">×</span> </button> </div> <div class="modal-body"> <div class="errors"></div> <p><strong>Which of the following best describes your feedback?</strong></p> <form method="post" style="overflow: hidden"> <div class="form-group"> <div class="radio"><label style="color: #121212;"><input type="radio" name="feedback-type" value="Recommendation"> Recommend</label></div><div class="radio"><label style="color: #121212;"><input type="radio" name="feedback-type" value="Problem"> Report a problem</label></div><div 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