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title="Mark as favorite" onclick="return false;"><i class="fa fa-star-o"></i></a> </h1> <ol class="breadcrumb"> <li><a href="../../../../biology.html"><i class="fa fa-home"></i></a><i class="fa fa-fw fa-chevron-right divider"></i></li><li><a href="../../470/08-metabolism-ahl.html">08 Metabolism AHL</a><i class="fa fa-fw fa-chevron-right divider"></i></li><li><span class="gray">Cell respiration 8.2 HL</span></li> <span class="pull-right" style="color: #555" title="Suggested study time: 30 minutes"><i class="fa fa-clock-o"></i> 30&apos;</span> </ol> <article id="main-article"> <style type="text/css">ol.breadcrumb { margin-bottom: 0 }</style><div id="toc-1675506064" class="toc"><a href="#" class="toc-switcher" title="Show table of contents"><small><i class="fa fa-reorder"></i> Table of contents <span class="pull-right"><i class="fa fa-chevron-down"></i></span></small></a><ol><li><a href="#header-1" class="scroll-to" data-target="header-1">Summary list for 8.2 Respiration</a></li><li><a href="#header-2" class="scroll-to" data-target="header-2">Mindmaps</a></li><li><a href="#header-3" class="scroll-to" data-target="header-3">Exam style question about cell respiration.</a></li><li><a href="#header-4" class="scroll-to" data-target="header-4">Model answer</a></li><li><a href="#header-5" class="scroll-to" data-target="header-5">Exam style question about mitochondria and respiration.</a></li><li><a href="#header-6" class="scroll-to" data-target="header-6">Model answer&nbsp;</a></li><li><a href="#header-7" class="scroll-to" data-target="header-7">Model answer</a><ol></ol></li><li><a href="#header-8" class="scroll-to" data-target="header-8"> 8.2 Cell respiration 1/1 </a></li></ol><li><a href="#header-9" class="scroll-to" data-target="header-9">Drag and drop activities</a></li></div><div class="intro-card" readonly="false"><img alt="" src="../../../images/02_molecules/respiration.png" style="float: left; width: 154px; height: 100px;">This topic looks at the details of glycolysis, the link reaction and the krebs cycle.&nbsp; The structure of mitochondria is related to its function and the amazing process of chemiosmosis is outlined leading to the production of water and ATP</div> <div class="panel panel-turquoise"> <div class="panel-heading"><a class="expander pull-right" href="#"><span class="fa fa-plus"></span></a> <div> <p>Key concepts</p> </div> </div> <div class="panel-body"> <div> <p>Learn and test your biological vocabulary using these <strong><a href="http://quizlet.com/76795952/flashcards" target="_blank">8.2 Cell respiration</a> </strong>flashcards.</p> <p style="text-align: center"><iframe height="500" src="https://quizlet.com/76795952/flashcards/embed?i=xxmo&x=1jj1" style="border:0" width="100%"></iframe></p> </div> </div> <div class="panel-footer"> <div> <p>text</p> </div> </div> </div> <div class="panel panel-default"> <div class="panel-footer"> <div> <p>text</p> </div> </div> </div> <div class="panel panel-yellow"> <div class="panel-heading"><a class="expander pull-right" href="#"><span class="fa fa-plus"></span></a> <div> <p>Essentials</p> </div> </div> <div class="panel-body"> <div> <p>These slides summarise the essential understanding and skills in this topic.&nbsp;<br> They contain short explanations in text and images - great revision.</p> <p>Read the slides and look up any words or details you find difficult to understand.</p> <div id="carousel-176" class="dynamic-gallery carousel slide" data-id="176"><div class="carousel-inner" role="listbox"><div class="item active"><a class="fancy" href="../../../../std-galleries/5-176/img0.jpg" data-fancybox="gallery-176" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-176/img0.jpg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-176/img1.jpg" data-fancybox="gallery-176" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-176/img1.jpg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-176/img2.jpg" data-fancybox="gallery-176" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-176/img2.jpg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-176/img3.jpg" data-fancybox="gallery-176" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-176/img3.jpg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-176/img4.jpg" data-fancybox="gallery-176" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-176/img4.jpg"></a></div></div><a class="left carousel-control" href="#carousel-176" role="button" data-slide="prev"><i class="fa fa-fw fa-chevron-left"></i></a><a class="right carousel-control" href="#carousel-176" role="button" data-slide="next"><i class="fa fa-fw fa-chevron-right"></i></a></div><ol class="std-carousel-indicators"><li data-index="0"><img title="Click to view" src="../../../../std-galleries/5-176/img0-thumb128.jpg"><li><li data-index="1"><img title="Click to view" src="../../../../std-galleries/5-176/img1-thumb128.jpg"><li><li data-index="2"><img title="Click to view" src="../../../../std-galleries/5-176/img2-thumb128.jpg"><li><li data-index="3"><img title="Click to view" src="../../../../std-galleries/5-176/img3-thumb128.jpg"><li><li data-index="4"><img title="Click to view" src="../../../../std-galleries/5-176/img4-thumb128.jpg"><li></li></ol> </div> </div> <div class="panel-footer"> <div> <p>These slides summarise the essential understanding and skills in this topic.&nbsp;<br> They contain short explanations in text and images - great revision.</p> <p>Read the slides and look up any words or details you find difficult to understand.</p> <div id="carousel-210" class="dynamic-gallery carousel slide" data-id="210"><div class="carousel-inner" role="listbox"><div class="item active"><a class="fancy" href="../../../../std-galleries/5-210/112movement-1.jpg" data-fancybox="gallery-210" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-210/112movement-1.jpg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-210/112movement-2.jpg" data-fancybox="gallery-210" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-210/112movement-2.jpg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-210/112movement-3.jpg" data-fancybox="gallery-210" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-210/112movement-3.jpg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-210/112movement-4.jpg" data-fancybox="gallery-210" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-210/112movement-4.jpg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-210/112movement-5.jpg" data-fancybox="gallery-210" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-210/112movement-5.jpg"></a></div></div><a class="left carousel-control" href="#carousel-210" role="button" data-slide="prev"><i class="fa fa-fw fa-chevron-left"></i></a><a class="right carousel-control" href="#carousel-210" role="button" data-slide="next"><i class="fa fa-fw fa-chevron-right"></i></a></div><ol class="std-carousel-indicators"><li data-index="0"><img title="Click to view" src="../../../../std-galleries/5-210/112movement-1-thumb128.jpg"><li><li data-index="1"><img title="Click to view" src="../../../../std-galleries/5-210/112movement-2-thumb128.jpg"><li><li data-index="2"><img title="Click to view" src="../../../../std-galleries/5-210/112movement-3-thumb128.jpg"><li><li data-index="3"><img title="Click to view" src="../../../../std-galleries/5-210/112movement-4-thumb128.jpg"><li><li data-index="4"><img title="Click to view" src="../../../../std-galleries/5-210/112movement-5-thumb128.jpg"><li></li></ol> </div> </div> </div> <div class="panel panel-violet"> <div class="panel-heading"><a class="expander pull-right" href="#"><span class="fa fa-plus"></span></a> <div> <p>Summary</p> </div> </div> <div class="panel-body"> <div> <h3 id="header-1">Summary list for 8.2 Respiration<small class="toc-back-button"><a href="#" class="scroll-to" data-target="toc-1675506064" title="Back to table of contents"><i class="fa fa-chevron-circle-up gray"></i></a></small></h3> <p><u>Introduction to reactions in respiration</u></p> <ul> <li class="liWithoutP">Cell respiration involves:</li> <li class="liWithoutP">the oxidation and reduction of electron carriers.</li> <li class="liWithoutP">the phosphorylation of molecules which makes them less stable.</li> <li class="liWithoutP">decarboxylation removes a carbon atom from a molecule.</li> </ul> <p><u>Glycolysis &amp; the Krebs cycle</u></p> <ul> <li>Glycolysis is the conversion of glucose to pyruvate in the cytoplasm giving a small net gain of ATP (without the use of oxygen).</li> <li>Aerobic cell respiration converts the pyruvate by decarboxylation and oxidation, into an acetyl compound.</li> <li>In the link reaction acetyl is attached to coenzyme A to form acetyl coenzyme A.</li> <li>In the Krebs cycle; <ul> <li>the oxidation of acetyl groups is coupled to the reduction of hydrogen carriers, liberating carbon dioxide.</li> <li>reduced NAD and FAD (NADH+H<sup>+</sup> and FADH<sup>+</sup>) carry energy released by oxidation reactions to the cristae of the mitochondria.</li> </ul> </li> </ul> <p><u>The electron transport chain &amp; Mitochondrion structure.</u></p> <ul> <li>the electron transport chain in the membrane of the cristae is coupled to proton pumping.</li> <li>oxygen is the final electron acceptor.</li> <li>In chemiosmosis protons diffuse through ATP synthase to generate ATP.</li> <li>Oxygen binds with the free protons to maintain the hydrogen gradient and resulting in the formation of water.</li> <li class="liWithoutP">The structure of the mitochondrion is adapted its function. Annotate a diagram of a mitochondrion to show these adaptations.</li> </ul> <div class="yellowBg"> <p><strong>Skills </strong></p> <ul> <li class="liWithoutP">Active mitochondria have been studies using electron tomography - images.</li> <li class="liWithoutP">students will be able to identify where decarboxylation and oxidation reactions occur in diagrams of the pathways of aerobic respiration.</li> <li class="liWithoutP"><strong>Guidance:</strong> The names of the intermediate compounds in glycolysis and the Krebs cycle are not required.</li> </ul> </div> <hr class="hidden-separator"> <h3 id="header-2">Mindmaps<small class="toc-back-button"><a href="#" class="scroll-to" data-target="toc-1675506064" title="Back to table of contents"><i class="fa fa-chevron-circle-up gray"></i></a></small></h3> <p>This diagram summaries the main sections of topic 8.2.<br> Test if you can draw something like these concept maps from memory.</p> <div id="carousel-175" class="dynamic-gallery carousel slide" data-id="175"><div class="carousel-inner" role="listbox"><div class="item active"><a class="fancy" href="../../../../std-galleries/5-175/82cellrespirationspiderlist.jpeg" data-fancybox="gallery-175" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-175/82cellrespirationspiderlist.jpeg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-175/82cellrespirationspidersimple.jpeg" data-fancybox="gallery-175" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-175/82cellrespirationspidersimple.jpeg"></a></div><div class="item "><a class="fancy" href="../../../../std-galleries/5-175/82cellrespirationspiderfull.jpeg" data-fancybox="gallery-175" title="" data-caption=""><img alt="" src="../../../../std-galleries/5-175/82cellrespirationspiderfull.jpeg"></a></div></div><a class="left carousel-control" href="#carousel-175" role="button" data-slide="prev"><i class="fa fa-fw fa-chevron-left"></i></a><a class="right carousel-control" href="#carousel-175" role="button" data-slide="next"><i class="fa fa-fw fa-chevron-right"></i></a></div><ol class="std-carousel-indicators"><li data-index="0"><img title="Click to view" src="../../../../std-galleries/5-175/82cellrespirationspiderlist-thumb128.jpg"><li><li data-index="1"><img title="Click to view" src="../../../../std-galleries/5-175/82cellrespirationspidersimple-thumb128.jpg"><li><li data-index="2"><img title="Click to view" src="../../../../std-galleries/5-175/82cellrespirationspiderfull-thumb128.jpg"><li></li></ol> </div> </div> <div class="panel-footer"> <div> <p>text</p> </div> </div> </div> <div class="panel panel-default"> <div class="panel-heading"><a class="expander pull-right" href="#"><span class="fa fa-plus"></span></a> <div> <p>Exam style questions</p> </div> </div> <div class="panel-body"> <div> <h3 id="header-3"><a id="erq1" name="erq1"></a>Exam style question about cell respiration.<small class="toc-back-button"><a href="#" class="scroll-to" data-target="toc-1675506064" title="Back to table of contents"><i class="fa fa-chevron-circle-up gray"></i></a></small></h3> <p>Explaining the link reaction is an important skill from this topic.</p> <p>Answer the question below, on a piece of paper, then check your answer against the model answer below.</p> <div class="yellowBg"> <p><strong>Compare and contrast the link reaction and the krebs cycle . [2]</strong></p> <p><strong>....................................................................................... ............................................................................ </strong></p> <p><strong>....................................................................................... ............................................................................ </strong></p> <p><strong>....................................................................................... ............................................................................ </strong></p> <p><strong>....................................................................................... ............................................................................ </strong></p> </div> <p>Click the + icon to see a model answer.</p> <button class="btn btn-xs bg-turquoise showhider"><i class="fa fa-fw fa-plus"></i></button><section class="hiddenbox hidden"> <div class="yellowBg"> <h3 id="header-4">Model answer<small class="toc-back-button"><a href="#" class="scroll-to" data-target="toc-1675506064" title="Back to table of contents"><i class="fa fa-chevron-circle-up gray"></i></a></small></h3> <ul> <li><span style="color:#FF0000;">The link reaction produces acetyl-CoA the Krebs cycle uses acetyl-CoA.</span></li> <li><span style="color:#FF0000;">The acetyl group reacts with CoA in the link reaction but it reacts with a with 4 carbon compound in the Krebs cycle.</span></li> <li><span style="color:#FF0000;">Both link reaction and the Krebs cycle occur in the mitochondria matrix.</span></li> </ul> </div> </section> <div class="panel panel-has-colored-body panel-expandable panel-has-border panel-default"> <div class="panel-heading"><a class="expander pull-right" href="#"><span class="fa fa-plus"></span></a> <div> <p>Extra exam style question on mitochondria. &nbsp; Click to open.</p> </div> </div> <div class="panel-body"> <div> <h3 id="header-5">Exam style question about mitochondria and respiration.<small class="toc-back-button"><a href="#" class="scroll-to" data-target="toc-1675506064" title="Back to table of contents"><i class="fa fa-chevron-circle-up gray"></i></a></small></h3> <p>The relationship between the structure and function of the mitochondrion is an important aspect of aerobic respiration.</p> <div class="yellowBg"> <p><b><span calibri="" style="font-size:11.0pt;line-height:107%; font-family:">Outline six ways in which the structure of a mitochondrion is related to its function. (6 marks)</span></b></p> <p style="text-align: center;"><img alt="" src="../../../images/richard/8.2-mitochondria%2C_mammalian_lung_-_tem.jpg" style="width: 157px; height: 152px;"><b><span calibri="" style="font-size:11.0pt;line-height:107%; font-family:"> </span></b></p> <hr> <hr> <hr> <hr> <hr> <hr> <p><em>Examiner&#39;s hint:&nbsp; In an &#39;Outline&#39; question give the most important points with an explanation or detail for each.</em></p> <p><em>Where there are six ways asked for it&#39;s best to try to outline seven, in case one point is incorrect.<br> Avoid any points which contradicts another.</em><em> Try to put the structural feature with the function.</em></p> </div> <p>Click the + icon to see a model answer &nbsp;</p> <button class="btn btn-xs bg-turquoise showhider"><i class="fa fa-fw fa-plus"></i></button><section class="hiddenbox hidden"> <h3 id="header-6">Model answer&nbsp;<small class="toc-back-button"><a href="#" class="scroll-to" data-target="toc-1675506064" title="Back to table of contents"><i class="fa fa-chevron-circle-up gray"></i></a></small></h3> <div class="yellowBg"> <p><strong>Outline 6 ways in which the structure of a mitochondrion is related to its function. (6 marks) </strong></p> <ul> <li><span style="color:#FF0000;">The outer membrane of the mitochondrion is permeable to oxygen and carbon dioxide which allows the exchange of these gases.</span></li> <li><span style="color:#FF0000;">The outer membrane has a transfer protein for pyruvate which brings pyruvate into the mitochondrion.</span></li> <li><span style="color:#FF0000;"><span style="color:#FF0000;">The inner membrane contains the electron carriers for the electron transfer chain.</span></span></li> <li><span style="color:#FF0000;"><span style="color:#FF0000;"></span>The inner membrane is folded into cristae to give a larger surface area for the electron transport chain.</span></li> <li><span style="color:#FF0000;">The double membrane creates an intermembrane space for hydrogen ions to accumulate.</span></li> <li><span style="color:#FF0000;">The electron carriers of the inner membrane pump hydrogen ions into the intermembrane space.</span></li> <li><span style="color:#FF0000;">The hydrogen pump creates a high hydrogen ion concentration/electrical potential gradient in the intermembrane space.</span></li> <li><span style="color:#FF0000;">The inner membrane is impermeable to hydrogen ions (except at ATP synthase).</span></li> <li><span style="color:#FF0000;"> ATP synthase embedded in the inner membrane allows the <span style="color:#FF0000;">protons to flow back </span><span style="color:#FF0000;">through </span>the inner membrane into the matrix.</span></li> <li><span style="color:#FF0000;">Proton flow through ATP synthase provides</span><span style="color:#FF0000;"> energy for ATP formation (by chemiosmosis).</span></li> <li><span style="color:#FF0000;">The matrix contains the enzymes of the Krebs cycle.</span></li> <li><span style="color:#FF0000;">The matrix contains microbial DNA (and ribosomes) to manufacture the enzymes of the Krebs cycle.</span></li> </ul> </div> </section> </div> </div> <div class="panel-footer"> <div> <p>text</p> </div> </div> </div> <div class="panel panel-has-colored-body panel-expandable panel-has-border panel-default"> <div class="panel-heading"> <div> <p>Extra exam question on the role of oxygen in aerobic respiration&nbsp; &nbsp; Click to open.</p> </div> </div> <div class="panel-body"> <div> <p>The role of oxygen in aerobic respiration is an important concept in this topic.</p> <p>Answer the question below, on a piece of paper, then check your answer against the model answer below.</p> <div class="yellowBg"> <p><strong>Describe the role of oxygen in the production of ATP aerobic respiration (4 marks).</strong></p> <hr> <hr> <hr> <hr><em>Hint: Your response must link the use of oxygen to the production of ATP.</em></div> Click on the &quot;+&quot; icon to see a model answer. <button class="btn btn-xs bg-turquoise showhider"><i class="fa fa-fw fa-plus"></i></button><section class="hiddenbox hidden"> <h3 id="header-7">Model answer<small class="toc-back-button"><a href="#" class="scroll-to" data-target="toc-1675506064" title="Back to table of contents"><i class="fa fa-chevron-circle-up gray"></i></a></small></h3> <div class="yellowBg"> <p><strong>Describe the role of oxygen in the production of ATP by aerobic respiration (4 marks).</strong></p> <ul> <li><span style="color:#FF0000;">Aerobic respiration produces ATP using a proton gradient and chemiosmosis.</span></li> <li><span style="color:#FF0000;">Creating the proton gradient requires a flow of electrons through the electron transport chain.</span></li> <li><span style="color:#FF0000;">Oxygen is the final electron acceptor.</span></li> <li><span style="color:#FF0000;">Allowing the maintenance of the proton gradient (flow of electrons) for the production of ATP.</span></li> <li><span style="color:#FF0000;"><span style="color:#FF0000;">When the protons pass through ATP synthase pores, they bind to oxygen.</span></span></li> <li><span style="color:#FF0000;">The protons, electrons and oxygen form water.</span></li> </ul> </div> </section> </div> </div> <div class="panel-footer"> <div>&nbsp;</div> </div> </div> </div> </div> <div class="panel-footer"> <div> <p>text</p> </div> </div> </div> <div class="panel panel-green"> <div class="panel-heading"><a class="expander pull-right" href="#"><span class="fa fa-plus"></span></a> <div> <p>Test yourself</p> </div> </div> <div class="panel-body"> <div> <p>This is a self marking quiz containing questions covering the topic outlined above.<br> Try the questions to check your understanding.</p> <br><a class="btn btn-primary btn-block text-center" data-toggle="modal" href="#9cb8f377"><i class="fa fa-play"></i> START QUIZ!</a><div class="modal fade modal-slide-quiz" id="9cb8f377"> <div class="modal-dialog" style="width: 95vw; max-width: 960px"> <div class="modal-content"> <div class="modal-header slide-quiz-title"> <h4 id="header-8"> 8.2 Cell respiration <strong class="q-number pull-right"> <span class="counter">1</span>/<span class="total">1</span> </strong> <small class="toc-back-button"><a href="#" class="scroll-to" data-target="toc-1675506064" title="Back to table of contents"><i class="fa fa-chevron-circle-up gray"></i></a></small></h4> </div> <div class="modal-body p-xs-3"> <div class="slide-quiz" data-stats="5-421-1196" style="opacity: 0"> <div class="exercise shadow-bottom"><div class="q-question"><p>What is the name given to the process where ATP provides phosphate for glucose in glycolysis?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Decarboxylation</label></p><p><label class="radio"><input type="radio"> Reduction</label></p><p><label class="radio"><input type="radio"> Lysis</label></p><p><label class="radio"><input class="c" type="radio"> Phosphorylation</label></p></div><div class="q-explanation"><p>This reaction can be callsed the phosphorylation of glucose.</p></div><div class="slide-q-actions"><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="exercise shadow-bottom"><div class="q-question"><p>What happens to a molecule which is said to be decarboxylated?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Dissolved carbon dioxide is released</label></p><p><label class="radio"><input class="c" type="radio"> Carbon is removed making carbon dioxide</label></p><p><label class="radio"><input type="radio"> Hydrogen is combined with carbon and oxygen.</label></p><p><label class="radio"><input type="radio"> Carbon is added from carbon dioxide.</label></p></div><div class="q-explanation"><p>Decarboxylation describes the removal of carbon from a molecule in a metabolic pathway.<br>This happens in the link reaction and also in the Krebs cycle.</p></div><div class="slide-q-actions"><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="exercise shadow-bottom"><div class="q-question"><p>The diagram below shows the process of glycolysis.</p><p><img alt="" src="../../../images/08_resp_photosn/glycolysis.png" style="width: 450px; height: 344px;"></p><p>What is the process happening in steps 7 and 8 of this process, eventually producing pyruvate?</p></div><div class="q-answer"><p><label class="radio"><input class="c" type="radio"> Dephosporylation</label></p><p><label class="radio"><input type="radio"> Dehydrogenation</label></p><p><label class="radio"><input type="radio"> Decarboxylation</label></p><p><label class="radio"><input type="radio"> Hydroxylation</label></p></div><div class="q-explanation"><p>Glycolysis involves the phosphorylation of molecules, e.g. glucose, which helps lysis.</p><p>Dephosphorylation removes phosphate from molecules in steps 7 and 8.</p></div><div class="slide-q-actions"><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="exercise shadow-bottom"><div class="q-question"><p>In which part of the cell does the Link reaction take place?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Cytoplasm</label></p><p><label class="radio"><input class="c" type="radio"> Matrix of mitochondria</label></p><p><label class="radio"><input type="radio"> rER</label></p><p><label class="radio"><input type="radio"> Inner membrane of mitochondria</label></p></div><div class="q-explanation"><p>The link reaction and the Krebs cycle take place in the matrix of the mitochondria</p></div><div class="slide-q-actions"><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="exercise shadow-bottom"><div class="q-question"><p>Which of the following statements is correct about the production of ATP during the stages of aerobic cell respiration?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Glycolysis uses up ATP</label></p><p><label class="radio"><input type="radio"> Chemiosmosis produces a small net gain of ATP.</label></p><p><label class="radio"><input type="radio"> No ATP is produced during the Krebs cycle.</label></p><p><label class="radio"><input class="c" type="radio"> Glycolysis produces a small net gain of ATP.</label></p></div><div class="q-explanation"><p>Glycolysis is the conversion of glucose to pyruvate in the cytoplasm giving a small net gain of ATP(without the use of oxygen.)</p></div><div class="slide-q-actions"><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="exercise shadow-bottom"><div class="q-question"><p>Where do the electrons go to after the electron transport chain of aerobic respiration?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Oxygen reacts with pyruvate.</label></p><p><label class="radio"><input type="radio"> Oxygen is needed for decarboxylation</label></p><p><label class="radio"><input class="c" type="radio"> Oxygen is the final electron acceptor.</label></p><p><label class="radio"><input type="radio"> Oxygen helps to reduce NAD</label></p></div><div class="q-explanation"><p>The electron transport chain in the membrane of the cristae is coupled to proton pumping.</p><p>Oxygen is the final electron acceptor.</p></div><div class="slide-q-actions"><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="exercise shadow-bottom"><div class="q-question"><p>What is the molecule which connects glycolysis and the link reaction?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Oxygen</label></p><p><label class="radio"><input type="radio"> Acetyl Co-A</label></p><p><label class="radio"><input type="radio"> NAD</label></p><p><label class="radio"><input class="c" type="radio"> Pyruvate</label></p></div><div class="q-explanation"><p>Pyruvate is the final product of glycolysis, this molecule is the first substrate of the link reaction.</p></div><div class="slide-q-actions"><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="exercise shadow-bottom"><div class="q-question"><p>What are the reactions which take place in the matrix of mitochondria?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Decarboxylation and chemiosmosis</label></p><p><label class="radio"><input type="radio"> Reduction of NAD and the electron transport chain</label></p><p><label class="radio"><input type="radio"> Glycolysis and the link reaction</label></p><p><label class="radio"><input class="c" type="radio"> Link reaction and Krebs cycle</label></p></div><div class="q-explanation"><p>The electron transport chain &amp; chemiosmosis take place on or in the mitochondrion inner membrane.</p><p>Glycolysis takes place in the cytoplasm.</p><p>The link reaction occurs in the matrix of the mitochondria as does the Krebs cycle.</p></div><div class="slide-q-actions"><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="exercise shadow-bottom"><div class="q-question"><p>What is the role of the enzyme ATP synthase in aerobic respiration?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> It performs the link reaction.</label></p><p><label class="radio"><input type="radio"> It reduces ATP using protons from chemiosmosis.</label></p><p><label class="radio"><input class="c" type="radio"> It generates ATP using the flow of protons in chemiosmosis.</label></p><p><label class="radio"><input type="radio"> It dephosphorulates ADP using energy from ATP.</label></p></div><div class="q-explanation"><p>In chemiosmosis protons diffuse through ATP synthase to generate ATP.</p><p>Oxygen binds with the free protons to maintain the hydrogen gradient and resulting in the formation of water.</p></div><div class="slide-q-actions"><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div> </div> </div> <div class="modal-footer slide-quiz-actions"> <div class=""> <div class="pull-left pull-xs-none mb-xs-3"> <button class="btn btn-default d-xs-none btn-prev"> <i class="fa fa-arrow-left"></i>&nbsp;&nbsp;Prev </button> </div> <div class="pull-right pull-xs-none"> <button class="btn btn-success btn-xs-block text-xs-center btn-results" style="display: none"> <i class="fa fa-bar-chart"></i> Check Results </button> <button class="btn btn-default d-xs-none btn-next"> Next&nbsp;&nbsp;<i class="fa fa-arrow-right"></i> </button> <button class="btn btn-default btn-xs-block text-xs-center btn-close" data-dismiss="modal" style="display: none"> Close </button> </div> </div> </div> </div> </div></div> </div> </div> <div class="panel-footer"> <div> <p>text</p> </div> </div> </div> <h3 id="header-9">Drag and drop activities<small class="toc-back-button"><a href="#" class="scroll-to" data-target="toc-1675506064" title="Back to table of contents"><i class="fa fa-chevron-circle-up gray"></i></a></small></h3> <p>Test your ability to construct biological explanations using the drag and drop questions below.</p> <div class="tib-quiz" data-stats="5-857-1196"><p>Test your knowledge of biological explanations using the drag and drop questions below.</p><p><strong>Summary of the generation of ATP by aerobic respiration.</strong></p><p>Note: This is a summary, it does not contain the details.</p><p>Drag and drop the correct term into the gap to describe a summary of ATP formation by oxidative phosphorylation.</p><div class="label label-default q-number">1</div><div class="exercise shadow-bottom"><div class="q-question"><p> </p><p class="gap-drop"> <span class="q-text-draggable draggable" draggable="true">carbon dioxide</span> <span class="q-text-draggable draggable" draggable="true">NAD</span> <span class="q-text-draggable draggable" draggable="true">oxygen</span> <span class="q-text-draggable draggable" draggable="true">oxidation</span> <span class="q-text-draggable draggable" draggable="true">protons</span> <span class="q-text-draggable draggable" draggable="true">oxidative phosphorylation</span> <span class="q-text-draggable draggable" draggable="true">synthase</span> <span class="q-text-draggable draggable" draggable="true">Calvin</span> <span class="q-text-draggable draggable" draggable="true">inner</span> <span class="q-text-draggable draggable" draggable="true">electrons</span> <span class="q-text-draggable draggable" draggable="true">Krebs</span> <span class="q-text-draggable draggable" draggable="true">outer</span> <span class="q-text-draggable draggable" draggable="true">acceptor</span> <span class="q-text-draggable draggable" draggable="true">potential</span></p></div><div class="q-answer"><p>Reduced <input type="text" style="height: auto;" data-c="NAD"> <span class="review"></span> and FAD produced in the <input type="text" style="height: auto;" data-c="Krebs"> <span class="review"></span> cycle donate <input type="text" style="height: auto;" data-c="electrons"> <span class="review"></span> to the electron transport chain (ETC) in the <input type="text" style="height: auto;" data-c="inner"> <span class="review"></span> mitochondrial membrane. These electrons are passed down the ETC in the membrane causing <input type="text" style="height: auto;" data-c="protons"> <span class="review"></span> to accumulate in the intermembrane space.</p><p>The accumulated protons pass through an ATP <input type="text" style="height: auto;" data-c="synthase"> <span class="review"></span> pore in the membrane into the stroma (chemiosmosis), losing electrical <input type="text" style="height: auto;" data-c="potential"> <span class="review"></span> energy which is used to drive the formation of ATP by <input type="text" style="height: auto;" data-c="oxidative phosphorylation"> <span class="review"></span> . The electrons and protons then combine with <input type="text" style="height: auto;" data-c="oxygen"> <span class="review"></span> to form water.</p><p>The ETC cannot function in the absence of oxygen as it is the final electron <input type="text" style="height: auto;" data-c="acceptor"> <span class="review"></span> at the end of the ETC.</p></div><div class="q-explanation"><p><em>Explanation: The ETC creates the proton gradient for ATP formation. The role of oxygen is to act as tyhe final electron acceptor for the ETC. </em></p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="totals"><span class="score"></span><button class="btn btn-success btn-block text-center check-total"><i class="fa fa-check-square-o"></i> Check</button></div></div><hr> <div class="panel panel-fucsia"> <div class="panel-heading"><a class="expander pull-right" href="#"><span class="fa fa-plus"></span></a> <div> <p>Just for fun</p> </div> </div> <div class="panel-body"> <div> <p>Everyone needs a bit of fun while they revise. 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