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to materials science </a></li><li><a href="../19519/metals-and-icp-spectroscopy-1.html">Metals and ICP spectroscopy</a></li><li><a href="../19541/catalysts--1.html">Catalysts </a></li><li><a href="../19580/liquid-crystals-1.html">Liquid crystals</a></li><li><a href="../19665/polymers--1.html">Polymers </a></li><li><a href="../19672/nanotechnology-1.html">Nanotechnology</a></li><li><a href="../19843/environmental-impact-plastics-1.html">Environmental impact - plastics</a></li><li><a href="../19858/superconducting-metals-x-ray-crystallography--1.html">Superconducting metals & X-ray crystallography </a></li><li><a href="../19666/condensation-polymers-1.html">Condensation polymers</a></li><li><a href="../19916/environmental-impact-heavy-metals-1.html">Environmental impact - heavy metals</a></li></ul></li><li class="selected"><a href="../19284/option-b--1.html" class="father">Option B </a><ul class="level-2"><li><a href="../19290/introduction-to-biochemistry--1.html">Introduction to 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href="../19411/nuclear-fusion-nuclear-fission-reactions-1.html">Nuclear fusion & nuclear fission reactions</a></li><li><a href="../19429/solar-energy-1.html">Solar energy</a></li><li><a href="../19437/environmental-impact-global-warming-1.html">Environmental impact - global warming</a></li><li><a href="../19453/electrochemistry-rechargeable-batteries-fuel-cells-1.html">Electrochemistry, rechargeable batteries & fuel cells</a></li><li><a href="../19458/nuclear-fusion-fission-hl--1.html">Nuclear fusion & fission (HL) </a></li><li><a href="../19470/photovoltaic-cells-and-dsscs-1.html">Photovoltaic cells and DSSCs</a></li></ul></li><li><a href="../19078/option-d-1.html" class="father">Option D</a><ul class="level-2"><li><a href="../19079/pharmaceutical-products-drug-action--1.html">Pharmaceutical products & drug action </a></li><li><a href="../19158/aspirin-penicillin--1.html">Aspirin & penicillin </a></li><li><a href="../19174/opiates-1.html">Opiates</a></li><li><a href="../19184/ph-regulation-of-the-stomach-1.html">pH regulation of the stomach</a></li><li><a href="../19194/antiviral-medications--1.html">Antiviral medications </a></li><li><a href="../19211/environmental-impact-of-some-medications-1.html">Environmental impact of some medications</a></li><li><a href="../19254/taxol-a-chiral-auxiliary-case-study-1.html">Taxol - a chiral auxiliary case study</a></li><li><a href="../19258/nuclear-medicine--1.html">Nuclear medicine </a></li><li><a href="../19273/drug-detection-analysis--1.html">Drug detection & analysis </a></li></ul></li></ul></li><li><a href="../16592/practical-scheme-of-work-ia--1.html">Practical scheme of work & IA </a><ul class="level-1"><li><a href="../16682/internal-assessment-1.html" class="father">Internal Assessment</a><ul class="level-2"><li><a href="../18892/scaffolding-the-investigation-1.html">'Scaffolding' the investigation</a></li><li><a href="../18896/timing-organisation--1.html">Timing & organisation </a></li><li><a href="../18905/choosing-the-research-question-1.html">Choosing the research question</a></li><li><a href="../18946/personal-engagement-1.html">Personal engagement</a></li><li><a href="../18950/exploration-1.html">Exploration</a></li><li><a href="../18957/analysis-1.html">Analysis</a></li><li><a href="../18965/evaluation-1.html">Evaluation</a></li><li><a href="../18966/communication-1.html">Communication</a></li><li><a href="../19882/internal-standardization-of-the-ia-1.html">Internal standardization of the IA</a></li><li><a href="../19901/submitting-the-samples-for-moderation-2.html">Submitting the samples for moderation</a></li><li><a href="../33754/ten-suggestions-for-ias-using-secondary-data-1.html">Ten suggestions for IAs using secondary data</a></li><li><a href="../37544/gaining-full-marks-for-a-databased-ia--1.html">Gaining full marks for a databased IA </a></li><li><a href="../19506/ia-example-marking-exercise--1.html">IA example & marking exercise </a></li><li><a href="../23929/genuine-examples-of-moderated-ia-reports-1.html">Genuine examples of moderated IA reports</a></li><li><a href="../25234/examples-of-teacher-marked-ia-reports--1.html">Examples of teacher-marked IA reports </a></li><li><a href="../37542/history-of-internal-assessment-1.html">History of Internal Assessment</a></li></ul></li><li><a href="../16598/mandatory-laboratory-components-1.html" class="father">Mandatory laboratory components</a><ul class="level-2"><li><a href="../16613/formula-of-magnesium-oxide--1.html">Formula of magnesium oxide </a></li><li><a href="../16612/determining-the-mr-of-an-unknown-gas-1.html">Determining the <i>M</i><sub>r</sub> of an unknown gas</a></li><li><a href="../16615/acid-base-titrations--1.html">Acid-base titrations </a></li><li><a href="../16616/a-green-acid-base-practical-1.html">A green acid-base practical</a></li><li><a href="../16617/analysis-of-aspirin-tablets-1.html">Analysis of aspirin tablets</a></li><li><a href="../16618/caco3-in-egg-shells-1.html">CaCO<sub>3</sub> in egg shells</a></li><li><a href="../16644/enthalpy-changes-1.html">Enthalpy changes</a></li><li><a href="../16631/reaction-rates-1.html">Reaction rates</a></li><li><a href="../16635/rate-dependent-factors-1.html">Rate-dependent factors</a></li><li><a href="../16636/determining-ea-for-a-reaction-1.html">Determining <i>E</i><sub>a</sub> for a reaction</a></li><li><a href="../16637/iodination-of-propanone-1.html">Iodination of propanone</a></li><li><a href="../18144/titrations-with-a-ph-meter-1.html">Titrations with a pH meter</a></li><li><a href="../18355/redox-titration-with-kmno4--1.html">Redox titration with KMnO<sub>4</sub> </a></li><li><a href="../16640/voltaic-cells-1.html">Voltaic cells</a></li><li><a href="../16659/3-d-molecular-modelling--1.html">3-D molecular modelling </a></li></ul></li><li><a href="../17168/other-good-practicals-1.html" class="father">Other good practicals</a><ul class="level-2"><li><a href="../17196/common-chemical-reactions-1.html">Common chemical reactions</a></li><li><a href="../227/elements-oxides-of-the-third-period--1.html">Elements & oxides of the third period </a></li><li><a href="../17239/the-halogens-1.html">The halogens</a></li><li><a href="../17162/boiling-points-of-mixtures-1.html">Boiling points of mixtures</a></li><li><a href="../17170/polarity-of-molecules-1.html">Polarity of molecules</a></li><li><a href="../18083/le-chateliers-principle--1.html">Le Chatelier's principle </a></li><li><a href="../19582/determining-kc-for-an-esterification-reaction-1.html">Determining <i>K</i><sub>c</sub> for an esterification reaction</a></li><li><a href="../18164/redox-reactions-of-vanadium--1.html">Redox reactions of vanadium </a></li><li><a href="../18351/chlorine-in-swimming-pools--1.html">Chlorine in swimming pools </a></li><li><a href="../18178/analysis-of-cuii-ions-in-solution--1.html">Analysis of Cu(II) ions in solution </a></li><li><a href="../18179/percentage-of-copper-in-brass-1.html">Percentage of copper in brass</a></li><li><a href="../18356/electrolytic-cells--1.html">Electrolytic cells </a></li><li><a href="../18598/reactions-of-organic-compounds-1.html">Reactions of organic compounds</a></li><li><a href="../18752/hydrolysis-of-halogenoalkanes-1.html">Hydrolysis of halogenoalkanes</a></li><li><a href="../18784/preparation-of-13-dinitrobenzene--1.html">Preparation of 1,3-dinitrobenzene </a></li><li><a href="../19022/determination-of-an-organic-structure-1.html">Determination of an organic structure</a></li><li><a href="../19887/preparation-of-nylon-66-1.html">Preparation of nylon 6,6</a></li><li><a href="../19343/determination-of-vitamin-c-content--1.html">Determination of vitamin C content </a></li><li><a href="../19342/hydrolysis-of-starch--1.html">Hydrolysis of starch </a></li><li><a href="../19159/preparation-purification-of-aspirin--1.html">Preparation & purification of aspirin </a></li></ul></li><li><a href="../18851/ict-in-practical-work-1.html" class="father">ICT in practical work</a><ul class="level-2"><li><a href="../18852/data-logging--1.html">Data logging </a></li><li><a href="../18853/software-for-graph-plotting--1.html">Software for graph plotting </a></li><li><a href="../18854/spreadsheets-for-data-processing--1.html">Spreadsheets for data processing </a></li><li><a href="../18855/databases-1.html">Databases</a></li><li><a href="../18856/computer-modelling-simulations--1.html">Computer modelling & simulations </a></li></ul></li><li><a href="../16594/group-4-project-1.html" class="father">Group 4 Project</a><ul class="level-2"><li><a href="../16595/practicalities-1.html">Practicalities</a></li><li><a href="../16596/reflective-statement--2.html">Reflective statement </a></li></ul></li><li><a href="../16666/a-new-laboratory-1.html">A new laboratory?</a></li></ul></li><li><a href="../16284/exams-1.html">Exams</a><ul class="level-1"><li><a href="../16286/essential-facts-1.html" class="father">Essential Facts</a><ul class="level-2"><li><a href="../16287/objectives-command-terms-1.html">Objectives & command terms</a></li><li><a href="../16288/grade-descriptors-1.html">Grade descriptors</a></li><li><a href="../16289/grade-boundaries-1.html">Grade boundaries</a></li></ul></li><li><a href="../16302/paper-1-multiple-choice-1.html" class="father">Paper 1 (Multiple Choice)</a><ul class="level-2"><li><a href="../16303/advice-to-students-paper-1-1.html">Advice to students (Paper 1)</a></li><li><a href="../31515/practice-paper-1-exams-1.html">Practice Paper 1 exams</a></li></ul></li><li><a href="../16305/paper-2-1.html" class="father">Paper 2</a><ul class="level-2"><li><a href="../16306/advice-to-students-paper-2-1.html">Advice to students (Paper 2)</a></li><li><a href="../16307/areas-of-difficulty-1.html">Areas of difficulty</a></li></ul></li><li><a href="../16313/paper-3--1.html" class="father">Paper 3 </a><ul class="level-2"><li><a 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href="../16323/retaking-the-exam-1.html">Retaking the exam</a></li></ul></li><li><a href="../16325/faqs-1.html">FAQs</a></li></ul></li><li><a href="../3147/ib-core-1.html">IB Core</a><ul class="level-1"><li><a href="../3149/learner-profile-1.html">Learner Profile</a></li><li><a href="../21735/extended-essays--1.html" class="father">Extended Essays </a><ul class="level-2"><li><a href="../21736/overview--1.html">Overview </a></li><li><a href="../21780/responsibilities-1.html">Responsibilities</a></li><li><a href="../21790/resources-1.html">Resources</a></li><li><a href="../21800/research-1.html">Research</a></li><li><a href="../21804/writing-the-essay-1.html">Writing the essay</a></li><li><a href="../21810/assessment-1.html">Assessment</a></li><li><a href="../22434/summary-of-advice--1.html">Summary of advice </a></li><li><a href="../25272/faqs--1.html">FAQs </a></li></ul></li><li><a href="../307/theory-of-knowledge-tok-1.html" class="father">Theory of Knowledge (TOK)</a><ul class="level-2"><li><a href="../41171/the-12-tok-concepts-1.html">The 12 TOK concepts</a></li><li><a href="../3507/why-tok-chemistry-1.html">Why TOK & Chemistry?</a></li><li><a href="../3505/a-modern-paradigm-1.html">A modern paradigm</a></li></ul></li></ul></li><li><a href="../17783/fast-track-to-tests-questions-1.html">Fast track to tests & questions</a><ul class="level-1"><li><a href="../17784/sl-multiple-choice-tests-on-individual-topics-1.html">SL Multiple choice tests on individual topics</a></li><li><a href="../24351/sl-multiple-choice-quizzes-on-sub-topics-1.html">SL Multiple choice 'quizzes' on sub-topics</a></li><li><a href="../31519/sl-practice-paper-1-exams-1.html">SL Practice Paper 1 exams</a></li><li><a href="../17786/sl-questions-on-each-sub-topic-1.html">SL Questions on each sub-topic</a></li><li><a href="../20431/sl-paper-3-section-a-questions-1.html">SL Paper 3 Section A questions</a></li><li><a href="../17792/sl-questions-on-the-options-1.html">SL Questions on the options</a></li><li><a href="../24897/sl-quizzes-on-option-sub-topics--1.html">SL Quizzes on option sub-topics </a></li><li><a href="../17785/hl-multiple-choice-tests-on-individual-topics-1.html">HL Multiple choice tests on individual topics</a></li><li><a href="../24352/hl-multiple-choice-quizzes-on-sub-topics-1.html">HL Multiple choice 'quizzes' on sub-topics</a></li><li><a href="../31520/hl-practice-paper-1-exams--1.html">HL Practice Paper 1 exams </a></li><li><a href="../17787/hl-questions-on-each-sub-topic--1.html">HL Questions on each sub-topic </a></li><li><a href="../20428/hl-paper-3-section-a-questions-1.html">HL Paper 3 Section A questions</a></li><li><a href="../17793/hl-questions-on-the-options-1.html">HL Questions on the options</a></li><li><a href="../24973/hl-quizzes-on-option-sub-topics-1.html">HL Quizzes on option sub-topics</a></li><li><a href="../41573/printable-versions-of-written-tasks--1.html">Printable versions of written tasks </a></li></ul></li><li><a href="../41465/complete-course-for-students--2.html">Complete course for students </a><ul class="level-1"><li><a href="../27988/full-coverage-of-each-topic-and-sub-topic-2.html" class="father">Full coverage of each topic and sub-topic</a><ul class="level-2"><li><a href="../27959/topic-1-stoichiometric-relationships-1.html">Topic 1 : Stoichiometric relationships</a></li><li><a href="../27960/topics-2-12-atomic-structure-1.html">Topics 2 & 12 : Atomic structure</a></li><li><a href="../27965/topics-3-13-periodicity-1.html">Topics 3 & 13 : Periodicity</a></li><li><a href="../27971/topics-4-14-chemical-bonding-structure-1.html">Topics 4 & 14 : Chemical bonding & structure</a></li><li><a href="../27987/topics-5-15-energeticsthermochemistry-1.html">Topics 5 & 15 : Energetics/thermochemistry</a></li><li><a href="../27995/topics-6-16-chemical-kinetics-1.html">Topics 6 & 16 : Chemical kinetics</a></li><li><a href="../28001/topics-7-17-equilibrium--1.html">Topics 7 & 17 : Equilibrium 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environment questions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../24866/biochemistry-the-environment-answers-1.html" title="Biochemistry & the environment answers">Biochemistry & the environment answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19336/proteins-enzymes-ahl--1.html" title="Proteins & enzymes (AHL) ">Proteins & enzymes (AHL) </a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../24962/mc-test-proteins-enzymes-ahl-1.html" title="MC test: Proteins & enzymes (AHL)">MC test: Proteins & enzymes (AHL)</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19341/proteins-enzymes-hl-questions--1.html" title="Proteins & enzymes (HL) questions ">Proteins & enzymes (HL) questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../24867/proteins-enzymes-hl-answers-1.html" title="Proteins & enzymes (HL) answers">Proteins & enzymes (HL) answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19347/nucleic-acids--1.html" title="Nucleic acids ">Nucleic acids </a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../24993/mc-test-nucleic-acids-1.html" title="MC test: Nucleic acids">MC test: Nucleic acids</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19360/nucleic-acids-questions--1.html" title="Nucleic acids questions ">Nucleic acids questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../24869/nucleic-acids-answers-1.html" title="Nucleic acids answers">Nucleic acids answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19361/biological-pigments--1.html" title="Biological pigments ">Biological pigments </a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25033/mc-test-biological-pigments-1.html" title="MC test: Biological pigments">MC test: Biological pigments</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19365/biological-pigments-questions--1.html" title="Biological pigments questions ">Biological pigments questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../24870/biological-pigments-answers-1.html" title="Biological pigments answers">Biological pigments answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19366/stereochemistry-in-biomolecules-1.html" title="Stereochemistry in biomolecules">Stereochemistry in biomolecules</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25034/mc-test-stereochemistry-in-biomolecules--1.html" title="MC test: Stereochemistry in biomolecules ">MC test: Stereochemistry in biomolecules </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19373/stereochemistry-in-biomolecules-questions-1.html" title="Stereochemistry in biomolecules questions">Stereochemistry in biomolecules questions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../24871/stereochemistry-in-biomolecules-answers--1.html" title="Stereochemistry in biomolecules answers ">Stereochemistry in biomolecules answers </a></li></ul></ul><li class=" parent" style="padding-left: 0px"><i class="expander fa fa-caret-right "></i><a href="../19390/option-c--1.html" title="Option C ">Option C </a></li><ul class="level-1 "><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19391/energy-sources-1.html" title="Energy sources">Energy sources</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25112/mc-test-energy-sources-1.html" title="MC test: Energy sources">MC test: Energy sources</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19404/energy-sources-questions--1.html" title="Energy sources questions ">Energy sources questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25025/energy-sources-answers-1.html" title="Energy sources answers">Energy sources answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19407/fossil-fuels-1.html" title="Fossil fuels">Fossil fuels</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25178/mc-test-fossil-fuels-1.html" title="MC test: Fossil fuels">MC test: Fossil fuels</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19312/fossil-fuels-questions--1.html" title="Fossil fuels questions ">Fossil fuels questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25123/fossil-fuels-answers--1.html" title="Fossil fuels answers ">Fossil fuels answers </a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19411/nuclear-fusion-nuclear-fission-reactions-1.html" title="Nuclear fusion & nuclear fission reactions">Nuclear fusion & nuclear fission reactions</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25188/mc-test-nuclear-fusion-nuclear-fission-reactions-1.html" title="MC test: Nuclear fusion & nuclear fission reactions">MC test: Nuclear fusion & nuclear fission reactions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19421/nuclear-fusion-nuclear-fission-questions-1.html" title="Nuclear fusion & nuclear fission questions">Nuclear fusion & nuclear fission questions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25180/nuclear-fusion-nuclear-fission-answers-1.html" title="Nuclear fusion & nuclear fission answers">Nuclear fusion & nuclear fission answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19429/solar-energy-1.html" title="Solar energy">Solar energy</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a 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global warming</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19450/environmental-impact-global-warming-questions--1.html" title="Environmental impact - global warming questions ">Environmental impact - global warming questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25190/environmental-impact-global-warming-answers-1.html" title="Environmental impact - global warming answers">Environmental impact - global warming answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19453/electrochemistry-rechargeable-batteries-fuel-cells-1.html" title="Electrochemistry, rechargeable batteries & fuel cells">Electrochemistry, rechargeable batteries & fuel cells</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25258/mc-test-electrochemistry-rechargeable-batteries-fuel-cells-1.html" title="MC test: Electrochemistry, rechargeable batteries & fuel cells">MC test: Electrochemistry, rechargeable batteries & fuel cells</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19455/electrochemistry-rechargeable-batteries-fuel-cells-questions-1.html" title="Electrochemistry, rechargeable batteries & fuel cells questions">Electrochemistry, rechargeable batteries & fuel cells questions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25204/electrochemistry-rechargeable-batteries-fuel-cells-answers-1.html" title="Electrochemistry, rechargeable batteries & fuel cells answers">Electrochemistry, rechargeable batteries & fuel cells answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19458/nuclear-fusion-fission-hl--1.html" title="Nuclear fusion & fission (HL) ">Nuclear fusion & fission (HL) </a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25269/mc-test-nuclear-fusion-nuclear-fission-hl-1.html" title="MC test: Nuclear fusion & nuclear fission (HL)">MC test: Nuclear fusion & nuclear fission (HL)</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19468/nuclear-fusion-fission-reactions-hl-questions--1.html" title="Nuclear fusion & fission reactions (HL) questions ">Nuclear fusion & fission reactions (HL) questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25205/nuclear-fusion-fission-reactions-hl-answers-1.html" title="Nuclear fusion & fission reactions (HL) answers">Nuclear fusion & fission reactions (HL) answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a 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title="Option D">Option D</a></li><ul class="level-1 "><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19079/pharmaceutical-products-drug-action--1.html" title="Pharmaceutical products & drug action ">Pharmaceutical products & drug action </a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25440/mc-test-pharmaceutical-products-drug-action-1.html" title="MC test: Pharmaceutical products & drug action">MC test: Pharmaceutical products & drug action</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19154/pharmaceutical-products-drug-action-questions--1.html" title="Pharmaceutical products & drug action questions ">Pharmaceutical products & drug action questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25270/pharmaceutical-products-drug-action-answers--1.html" title="Pharmaceutical products & drug action answers ">Pharmaceutical products & drug action answers </a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19158/aspirin-penicillin--1.html" title="Aspirin & penicillin ">Aspirin & penicillin </a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25684/mc-test-aspirin-penicillin-1.html" title="MC test: Aspirin & penicillin">MC test: Aspirin & penicillin</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19171/aspirin-penicillin-questions-1.html" title="Aspirin & penicillin questions">Aspirin & penicillin questions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25313/aspirin-penicillin-answers--1.html" title="Aspirin & penicillin answers ">Aspirin & penicillin answers </a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19174/opiates-1.html" title="Opiates">Opiates</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25494/mc-test-opiates-1.html" title="MC test: Opiates">MC test: Opiates</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19176/opiates-questions-1.html" title="Opiates questions">Opiates questions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25356/opiates-answers--1.html" title="Opiates answers ">Opiates answers </a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19184/ph-regulation-of-the-stomach-1.html" title="pH regulation of the stomach">pH regulation of the stomach</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25683/mc-test-ph-regulation-of-the-stomach-1.html" title="MC test: pH regulation of the stomach">MC test: pH regulation of the stomach</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19185/ph-regulation-of-the-stomach-questions--1.html" title="pH regulation of the stomach questions ">pH regulation of the stomach questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25391/ph-regulation-of-the-stomach-answers-1.html" title="pH regulation of the stomach answers">pH regulation of the stomach answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19194/antiviral-medications--1.html" title="Antiviral medications ">Antiviral medications </a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25685/mc-test-antiviral-medications-1.html" title="MC test: Antiviral medications">MC test: Antiviral medications</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19195/antiviral-medications-questions-1.html" title="Antiviral medications questions">Antiviral medications questions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25521/antiviral-medications-answers--1.html" title="Antiviral medications answers ">Antiviral medications answers </a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19211/environmental-impact-of-some-medications-1.html" title="Environmental impact of some medications">Environmental impact of some medications</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a 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class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25687/mc-test-taxol-a-chiral-auxiliary-case-study-1.html" title="MC test: Taxol - a chiral auxiliary case study">MC test: Taxol - a chiral auxiliary case study</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../19256/taxol-questions--1.html" title="Taxol questions ">Taxol questions </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../25638/taxol-answers-1.html" title="Taxol answers">Taxol answers</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a href="../19258/nuclear-medicine--1.html" title="Nuclear medicine ">Nuclear medicine </a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a href="../26020/mc-test-nuclear-medicine-1.html" title="MC test: Nuclear 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</div><section id="main-content"><div id="toc-1672969674" class="toc"><a href="#" class="toc-switcher" title="Show table of contents"><small><i class="fa fa-reorder"></i> Table of contents <span class="pull-right"><i class="fa fa-chevron-down"></i></span></small></a></div><h1><img class="ico" src="../../../img/icons/standard-1.png"> <img class="ico" src="../../../img/icons/higher-1.png"> B.5 Vitamins (1 hour)</h1><div class="pinkBg"><div><h2>Pause for thought</h2><p><img alt="" class="noborder" src="../../../ib/chemistry/images/2014-Options/Option-B/Shane-Warne.jpg" style="width: 220px; height: 330px; float: right;"><br>In the 1970s <a href="http://www.nobelprize.org/nobel_prizes/chemistry/laureates/1995/">Frank Rowland and Mario Molina</a> predicted that CFCs would interfere with the ozone layer. Their work was treated with scepticism, but in 1985 satellite evidence showed that the depletion of ozone above the Antarctic was in fact much greater than had been predicted. This coincided with a rise in the number of cases of skin cancer in countries like Australia and New Zealand due to the increasing amounts of ultraviolet radiation reaching the surface of the Earth. In order to protect their skin from exposure Australians stated to apply sunblock whenever they were out in the sun. However by trying to avoid one health problem they have inadvertently brought about a serious vitamin deficiency problem. Very few foods contain vitamin D and the body normally obtains its vitamin D through the action of the ultraviolet light from the sun with cholesterol in the skin. A lack of vitamin D leads to rickets and osteoporosis.</p><p>Even though it is now mandatory in Australia to fortify edible oils and spreads with vitamin D, it has been <a href="http://www.biomedcentral.com/1471-2458/14/1001">reported in 2014</a> that 25% of all Australians are suffering from vitamin D deficiency. In order to counterbalance this lack of vitamin D, many Australians have taken to buying vitamin D supplements (or multi-vitamin supplements which contain vitamin D) and it is <a href="http://www.hindawi.com/journals/jnme/2014/374208/">reported </a>that the sale of such supplements increased three-fold during the decade 2001 to 2010.</p><p>Trying to balance the negative effects of too much sunlight with the negative effects of too little sunlight is no easy task.</p><hr class="hidden"></div></div><hr class="hidden"><div class="box"><h2>Nature of Science</h2><p>The explanation of deficiency diseases (e.g. scurvy and beriberi) in terms of lack of specific vitamins (vital amines) was due to scientists seeking a cause for specific observations.</p><hr class="hidden"></div><hr class="hidden"><div class="box"><table align="left" border="0" cellpadding="10" cellspacing="0"><tbody><tr><td style="width: 50%;" valign="top"><h3><b><span style="font-weight: normal; "></span></b></h3><div class="yellowBg"><div><h2><b><span style="font-weight: normal; "><strong>Learning outcomes</strong></span></b></h2><p>After studying this topic students should be able to:</p><p><strong>Understand:</strong></p><ul><li>Vitamins are organic micronutrients which must be obtained from suitable food sources, as (mostly) they cannot be synthesized by the body.</li><li>The structure of a vitamin can be used to predict whether the vitamin is soluble in water or fat.</li><li>Most vitamins are sensitive to heat.</li><li>Particular diseases caused by a lack of specific vitamins in the diet affect millions of people worldwide.</li></ul><hr class="hidden"><p><strong>Apply their knowledge to:</strong></p><ul><li>Compare the structures of vitamins A, C and D.</li><li>Discuss the causes and effects of vitamin deficiencies in different countries and suggest possible solutions.</li></ul></div></div></td><td style="width: 50%;" valign="top"><h4><b><span style="font-weight: normal;"></span></b></h4><div class="yellowBg"><div><h4><b><span style="font-weight: normal;"><strong>Clarification notes</strong></span></b></h4><p>The structures of vitamins A, C and D are given in Section 35 of the data booklet.<br><br><span style="color:#FF0000;">Note that vitamin A is technically a group of vitamins. The data booklet shows just the structure of retinol for vitamin A, but retinal, which is covered in sub-topic B.9, is also a form of vitamin A.</span></p><hr class="hidden"><p>Specific food sources of vitamins and the names of vitamin deficiency diseases are not required to be learned.</p><hr class="hidden"><h4>International-mindedness</h4><p>The sale of vitamin pills (and the food supplements industry in general) has become a very lucrative business in many countries.</p><hr class="hidden"><p>There is an increase in Vitamin D deficiency, partly because humans protect their skin more from sunlight.</p></div></div></td></tr></tbody></table></div><hr class="hidden"><div class="box"><table align="left" border="0" cellpadding="10" cellspacing="0"><tbody><tr><td style="width: 50%;" valign="top"><h2><span style=""><b><span style="font-weight: normal;"><strong>Teaching tips</strong></span></b></span></h2><p>Much of this topic is simply factual information that students will need to learn. This is particularly true for the last part which looks at the causes and effects of nutrient deficiencies and possible ways of overcoming these problems. The syllabus states that specific food sources and the names of particular diseases caused by vitamin deficiency do not need to be learned but it is hard to see how the causes, effects and possible solutions can be discussed by students without mentioning some of the common names.</p><p>The understanding really comes in when the structures are compared. Retinol (vitamin A) is essentially a long hydrocarbon chain and, although a molecule of retinol does contains a single polar -OH group, overall it is virtually non-polar so will be fat-soluble. It is probably also worth mentioning that it is coloured due to the large amount of conjugation of the double bonds, although this is really covered in B.9: Biological pigments..</p><p>Calciferol (vitamin D) also contains a single -OH group but again it is essentially a large hydrocarbon molecule with a structure that is almost (but not quite, as one of the rings is not closed) a steroid. Like retinol it is largely non-polar so the London dispersion forces of attraction between molecules of calciferol make it insoluble in water but soluble in fat.</p><p>Ascorbic acid (vitamin C) is very different. Ascorbic acid is quite polar as it contains several -OH groups so can readily hydrogen bond to water molecules whereas it is insoluble in fat. Because it is soluble in water it is not retained by the body hence the need for fresh fruit etc. as a replacement source of vitamin C. Aspects of vitamin C obviously provide considerable scope for topics for the Individual Scientific Investigation.</p><hr class="hidden"></td><td style="width: 50%;" valign="top"><h4><b><span style="font-weight: normal; "><strong>Study guide</strong></span></b></h4><p style="margin: 0px 0px 1em; padding: 0px; color: rgb(0, 0, 0); font-size: 1em;"><a href="http://ukcatalogue.oup.com/product/education/international/ibdiploma/studyguides/9780199151424.do?"><b><span style="font-weight: normal;"><img alt="" class="left noborder" src="../../../ib/chemistry/images/2014%20Basic%20information/New%20cover.jpg" style="width: 67px; height: 96px;"></span></b></a></p><p style="margin: 0px 0px 1em; padding: 0px; color: rgb(0, 0, 0); font-size: 1em;"></p><hr class="hidden"><p><b><span style="font-weight: normal;">Page 1</span></b><span style="font-weight: normal;">31</span><b><span style="font-weight: normal;"> </span></b></p><p style="margin: 0px 0px 1em; padding: 0px; color: rgb(0, 0, 0); font-size: 1em;"></p><hr class="hidden"><h2>Questions</h2><p>For ten 'quiz' questions (for quick testing of knowledge and understanding with the answers explained) see <a href="../24829/mc-test-vitamins-1.html" title="Options » Option B » Vitamins » MC test: Vitamins">MC test: Vitamins</a>.</p><p>For short-answer questions see <a href="../19410/vitamins-questions--1.html" title="Options » Option B » Vitamins » Vitamins questions ">Vitamins questions</a> together with the worked answers on a separate page <a href="../24865/vitamins-answers-1.html" title="Options » Option B » Vitamins » Vitamins answers">Vitamins answers</a>.</p><hr class="hidden"><h4><span style=""><b><span style="font-weight: normal;"><strong>Vocabulary list:</strong></span></b></span></h4><p>micronutrient<br>vitamin A (retinol)<br>vitamin D (calciferol)<br>vitamin C (ascorbic acid)<br>xerophthalmia<br>osteoporosis<br>rickets<br>scurvy</p><hr class="hidden"><h2><strong>Practical work</strong></h2><p><a href="../19343/determination-of-vitamin-c-content--1.html"><img class="ico" src="../../../img/icons/lab-1.png"> Determination of Vitamin C content </a></p><hr class="hidden"><h4></h4></td></tr></tbody></table></div><hr class="hidden"><div class="greenBg"><h2 id="header-13">Teaching slides</h2><p>Teachers may wish to share these slides with students for learning or for reviewing key concepts.</p><div id="myCarousel-14" class="carousel slide" data-id="458"><!-- Carousel items --><div class="carousel-inner"><div class="active item"><a class="fancy" href="../../../tib-galleries/3-458/b57.png" rel="gallery-458" title=""><img alt="" src="files/tib-galleries/3-458/b57.png"></a><div class="carousel-caption"><p>Vitamins: </p></div></div><div class="item"><a class="fancy" href="../../../tib-galleries/3-458/b51.png" rel="gallery-458" title=""><img alt="" src="files/tib-galleries/3-458/b51.png"></a><div class="carousel-caption"><p>Vitamins: </p></div></div><div class="item"><a class="fancy" href="../../../tib-galleries/3-458/b52.png" rel="gallery-458" title=""><img alt="" src="files/tib-galleries/3-458/b52.png"></a><div class="carousel-caption"><p>Vitamins: </p></div></div><div class="item"><a class="fancy" href="../../../tib-galleries/3-458/b53.png" rel="gallery-458" title=""><img alt="" src="files/tib-galleries/3-458/b53.png"></a><div class="carousel-caption"><p>Vitamins: </p></div></div><div class="item"><a class="fancy" href="../../../tib-galleries/3-458/b54.png" rel="gallery-458" title=""><img alt="" src="files/tib-galleries/3-458/b54.png"></a><div class="carousel-caption"><p>Vitamins: </p></div></div><div class="item"><a class="fancy" href="../../../tib-galleries/3-458/b55.png" rel="gallery-458" title=""><img alt="" src="files/tib-galleries/3-458/b55.png"></a><div class="carousel-caption"><p>Vitamins: </p></div></div><div class="item"><a class="fancy" href="../../../tib-galleries/3-458/b7.png" rel="gallery-458" title=""><img alt="" src="files/tib-galleries/3-458/b7.png"></a><div class="carousel-caption"><p>Vitamins: </p></div></div></div><!-- Carousel nav --><a class="carousel-control left" href="#myCarousel-14" data-slide="prev">‹</a><a class="carousel-control right" href="#myCarousel-14" data-slide="next">›</a><div class="tib-indicators"><img class="" title="Click to view" style="margin: 10px 4px; width: 48px; height: 48px;" alt="" src="files/tib-galleries/3-458/b57-thumb128.jpg"><img class="" title="Click to view" style="margin: 5px 4px; width: 48px; height: 48px;" alt="" src="files/tib-galleries/3-458/b51-thumb128.jpg"><img class="" title="Click to view" style="margin: 5px 4px; width: 48px; height: 48px;" alt="" src="files/tib-galleries/3-458/b52-thumb128.jpg"><img class="" title="Click to view" style="margin: 5px 4px; width: 48px; height: 48px;" alt="" src="files/tib-galleries/3-458/b53-thumb128.jpg"><img class="" title="Click to view" style="margin: 5px 4px; width: 48px; height: 48px;" alt="" src="files/tib-galleries/3-458/b54-thumb128.jpg"><img class="" title="Click to view" style="margin: 5px 4px; width: 48px; height: 48px;" alt="" src="files/tib-galleries/3-458/b55-thumb128.jpg"><img class="" title="Click to view" style="margin: 5px 4px; width: 48px; height: 48px;" alt="" src="files/tib-galleries/3-458/b7-thumb128.jpg"></div></div><p> </p></div><hr class="hidden"><div class="blueBg"><h2><span style="font-weight: bold;">Other resources</span></h2><p>Unfortunately vitamins are big business so a search of 'vitamins' on the web and YouTube produces much that is useless from a scientific viewpoint.</p><p><strong>1.</strong> A couple of reasonable sites for some information on vitamins are one from a <a href="http://www.brianmac.co.uk/vitamins.htm">sports coach</a> and one from <a href="http://www.netdoctor.co.uk/health_advice/facts/vitamins_which.htm">netdoctor</a>.</p><hr class="hidden"><p><strong>2.</strong> The benefits of vitamin D and the problems of vitamin D deficiency.</p><p style="text-align: center;"><iframe allowfullscreen="" frameborder="0" height="280" src="//www.youtube.com/embed/g-72k7h8WYI?rel=0" width="360"></iframe></p><p style="text-align: center;"><a href="http://youtu.be/g-72k7h8WYI" target="_blank" title="Videos"><img class="ico" src="../../../img/icons/video-1.png"><span class="anchor" id="video-1" name="video-1"> </span> Vitamin D deficiency</a></p><hr class="hidden"><p style="text-align: center;"></p></div></section></article><section id="media-extras"><div class="page-actions no-print navbar inline hidden-desktop"><div class="navbar-inner"><ul class="nav"><li><a class="presentation" href="#" onclick="return false;"><i class="fa fa-desktop"></i></a></li><li><a class="print-section-blog" href="#" onclick="return false;"><i class="fa fa-print"></i></a></li><li><a class="page-bookmarker" data-ticket="IB Docs (2) Team" data-pid="19305" href="#" onclick="return false;"><i class="fa fa-star"></i></a></li><li><a class="personal-notes" href="#" onclick="return false;"><i class="fa fa-file-text"></i></a></li><li><a class="" data-toggle="modal" href="#modal-feedback" onclick="return false;"><i class="fa fa-envelope-o"></i></a></li><li class="dropdown"><a class="dropdown-toggle" data-toggle="dropdown" data-target="#" href="#"><i class="fa fa-share-alt"></i></a><ul class="dropdown-menu" role="menu"><li><a class="" target="_blank" title="Share on Twitter" href="https://twitter.com/share?text=%22Vitamins+++%22+-+via+%40InThinker+%23chemistry%0A&url=https%3A%2F%2Fwww.thinkib.net%2Fchemistry%2Fpage%2F19305%2Fvitamins-"><i class="fa fa-twitter-square"></i><span>Twitter</span></a></li><li><a class="" target="_blank" title="Share on Facebook" href="https://www.facebook.com/sharer.php?u=https%3A%2F%2Fwww.thinkib.net%2Fchemistry%2Fpage%2F19305%2Fvitamins-&t=Vitamins+++"><i class="fa fa-facebook-square"></i><span>Facebook</span></a></li><li><a class="" href="http://www.linkedin.com/shareArticle?mini=true&url=https%3A%2F%2Fwww.thinkib.net%2Fchemistry%2Fpage%2F19305%2Fvitamins-"><i class="fa fa-linkedin-square"></i><span>LinkedIn</span></a></li><li><a class="" href="https://plus.google.com/share?url=https%3A%2F%2Fwww.thinkib.net%2Fchemistry%2Fpage%2F19305%2Fvitamins-"><i class="fa fa-google-plus-square"></i><span>Google +</span></a></li><li><a class="" href="mailto:?subject=Vitamins &body=In the 1970s Frank Rowland and Mario Molina predicted that CFCs would interfere with the ozone layer. 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