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genes & alleles">Chromosomes genes & alleles</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17822/human-genome-project.html" title="Human Genome Project">Human Genome Project</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17827/base-substitution-mutation.html" title="Base substitution mutation">Base substitution mutation</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17859/chromosomes.html" title="Chromosomes">Chromosomes</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17816/karyograms-and-non-disjunction.html" title="Karyograms and non-disjunction">Karyograms and non-disjunction</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17814/introduction-to-meiosis.html" title="Introduction to Meiosis">Introduction to Meiosis</a></li><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17817/theoretical-genetics-1.html" title="Theoretical Genetics 1">Theoretical Genetics 1</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../23787/stargardt-disease.html" title="Stargardt disease">Stargardt disease</a></li></ul><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17818/theoretical-genetics-2.html" title="Theoretical Genetics 2">Theoretical Genetics 2</a></li><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17819/sex-linked-genes.html" title="Sex Linked Genes">Sex Linked Genes</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../17825/is-genetics-an-embarrassment-to-biology-education-.html" title="Is genetics an embarrassment to biology education? ">Is genetics an embarrassment to biology education? </a></li></ul><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17809/hairy-hands-genetics-of-mid-digital-hair.html" title="Hairy Hands - genetics of mid-digital hair">Hairy Hands - genetics of mid-digital hair</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17810/pedigree-chart-phenotype-ratios.html" title="Pedigree Chart & Phenotype Ratios">Pedigree Chart & Phenotype Ratios</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17820/ia-maize-genetics-experiment.html" title="IA Maize Genetics Experiment">IA Maize Genetics Experiment</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17823/genetically-modified-organisms.html" title="Genetically Modified Organisms.">Genetically Modified Organisms.</a></li><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17824/introduction-to-cloning.html" title="Introduction to Cloning.">Introduction to Cloning.</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../33736/cloning-ethics-quiz.html" title="Cloning ethics - quiz">Cloning ethics - quiz</a></li></ul><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17811/therapeutic-cloning-debate-.html" title="Therapeutic Cloning Debate ">Therapeutic Cloning Debate </a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../16981/ecology-activities-for-learning.html" title="Ecology Activities for Learning">Ecology Activities for Learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17905/ecological-terms.html" title="Ecological terms.">Ecological terms.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17906/food-webs.html" title="Food Webs">Food Webs</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17927/mesocosm-lab.html" title="Mesocosm Lab">Mesocosm Lab</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../23435/ecology-mini-investigation.html" title="Ecology mini investigation">Ecology mini investigation</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../33629/ecology-field-trip-at-home.html" title="Ecology field trip - at home">Ecology field trip - at home</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17907/energy-flow.html" title="Energy Flow.">Energy Flow.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17912/carbon-cycle-skills.html" title="Carbon Cycle Skills">Carbon Cycle Skills</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17908/enhanced-greenhouse-effect.html" title="Enhanced Greenhouse Effect.">Enhanced Greenhouse Effect.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17909/climate-change.html" title="Climate Change.">Climate Change.</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../16985/evolution-activities-for-learning.html" title="Evolution: Activities for Learning">Evolution: Activities for Learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../15988/evolution-introduction.html" title="Evolution introduction">Evolution introduction</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../15990/variation-overproduction.html" title="Variation & overproduction">Variation & overproduction</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../15989/evolution-examples.html" title="Evolution examples">Evolution examples</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19320/classification-binomial-names.html" title="Classification & binomial names">Classification & binomial names</a></li><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../15991/classification-of-plants.html" title="Classification of Plants">Classification of Plants</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../19306/plant-classification-quiz.html" title="Plant classification quiz">Plant classification quiz</a></li></ul><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../15993/classification-of-animals.html" title="Classification of Animals">Classification of Animals</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../23751/classification-games.html" title="Classification games">Classification games</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18912/intro-to-cladistics.html" title="Intro to cladistics">Intro to cladistics</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18910/reclassification-of-figworts-using-cladistics.html" title="Reclassification of figworts using cladistics">Reclassification of figworts using cladistics</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../18027/humans-activities-for-learning.html" title="Humans Activities for Learning">Humans Activities for Learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18028/digestion-enzymes-intro-.html" title="Digestion & Enzymes Intro ">Digestion & Enzymes Intro </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18029/ia-lipase-experiment.html" title="IA Lipase Experiment">IA Lipase Experiment</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18033/structure-of-the-digestive-system.html" title="Structure of the digestive system.">Structure of the digestive system.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18030/intestine-structure-function.html" title="Intestine Structure & Function.">Intestine Structure & Function.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18031/blood-and-blood-vessels.html" title="Blood and Blood Vessels">Blood and Blood Vessels</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18032/heart-dissection-diagram.html" title="Heart Dissection & Diagram">Heart Dissection & Diagram</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18026/controlling-heartbeat.html" title="Controlling Heartbeat">Controlling Heartbeat</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18590/blood-clotting-and-heart-disease.html" title="Blood clotting and heart disease.">Blood clotting and heart disease.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18117/antigens-and-antibodies-.html" title="Antigens and antibodies ">Antigens and antibodies </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18180/hiv-and-aids.html" title="HIV and AIDS">HIV and AIDS</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18116/immune-system-.html" title="Immune System ">Immune System </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18115/alveoli-gas-exchange.html" title="Alveoli & gas exchange">Alveoli & gas exchange</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19330/ventilation-lung-disease.html" title="Ventilation & lung disease">Ventilation & lung disease</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18421/nerve-impulses.html" title="Nerve impulses.">Nerve impulses.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18461/synapses.html" title="Synapses">Synapses</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../31311/chemicals-which-affect-synapses.html" title="Chemicals which affect synapses">Chemicals which affect synapses</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19886/hormones-introduction.html" title="Hormones introduction">Hormones introduction</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19894/homeostasis-of-glucose.html" title="Homeostasis of Glucose.">Homeostasis of Glucose.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19907/harvey-and-the-search-for-ova.html" title="Harvey and the search for ova">Harvey and the search for ova</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19908/hormones-and-the-menstrual-cycle.html" title="Hormones and the menstrual cycle">Hormones and the menstrual cycle</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19927/hormones-in-ivf.html" title="Hormones in IVF">Hormones in IVF</a></li></ul></ul><li class=" parent std-toplevel" style="padding-left: 4px"><i class="expander fa fa-caret-right "></i><a class="" href="../17178/additional-hl.html" title="Additional HL">Additional HL</a></li><ul class="level-1 "><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17917/hl-nucleic-acids-activities-for-learning.html" title="HL Nucleic Acids Activities for Learning">HL Nucleic Acids Activities for Learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17918/dna-structure-extras-for-hl.html" title="DNA structure - Extras for HL">DNA structure - Extras for HL</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../16141/dna-replication-for-hl-students.html" title="DNA Replication for HL Students">DNA Replication for HL Students</a></li><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17920/transcription-extras-for-hl.html" title="Transcription - extras for HL">Transcription - extras for HL</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../37259/extension-concept-hydrolysis-of-atp.html" title="Extension concept - Hydrolysis of ATP">Extension concept - Hydrolysis of ATP</a></li></ul><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18048/translation-ribosomes.html" title="Translation & ribosomes">Translation & ribosomes</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17921/four-levels-of-protein-structure.html" title="Four levels of protein structure">Four levels of protein structure</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../18211/hl-metabolism-activities-for-learning.html" title="HL Metabolism Activities for Learning">HL Metabolism Activities for Learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19840/activation-energy-and-enzyme-pathways.html" title="Activation energy and enzyme pathways">Activation energy and enzyme pathways</a></li><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19850/emergency-room-activity-enzyme-inhibition.html" title="Emergency room activity - enzyme inhibition">Emergency room activity - enzyme inhibition</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../19865/toxicology-training-course.html" title="Toxicology training course">Toxicology training course</a></li></ul><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17923/end-product-inhibition-of-enzymes.html" title="End product inhibition of Enzymes.">End product inhibition of Enzymes.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17922/hl-respiration-introduction.html" title="HL Respiration introduction">HL Respiration introduction</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../16207/glycolysis-and-the-krebs-cycle.html" title="Glycolysis and the Krebs Cycle">Glycolysis and the Krebs Cycle</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18214/electron-transport-chain.html" title="Electron transport chain">Electron transport chain</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../16209/chloroplasts-and-photosynthesis.html" title="Chloroplasts and Photosynthesis">Chloroplasts and Photosynthesis</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../16210/light-dependent-reactions.html" title="Light Dependent Reactions">Light Dependent Reactions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../16211/light-independent-reactions.html" title="Light Independent Reactions">Light Independent Reactions</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17720/hl-plant-biology-activities-for-learning.html" title="HL Plant Biology - Activities for Learning">HL Plant Biology - Activities for Learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17726/leaf-stomata-transpiration.html" title="Leaf stomata & transpiration">Leaf stomata & transpiration</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17721/vascular-tissues-introduction.html" title="Vascular tissues - introduction">Vascular tissues - introduction</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17723/transport-in-xylem.html" title="Transport in xylem">Transport in xylem</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17727/experiments-on-transpiration.html" title="Experiments on Transpiration.">Experiments on Transpiration.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17724/transpiration-and-xerophytes-.html" title="Transpiration and Xerophytes ">Transpiration and Xerophytes </a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17763/phloem-and-translocation.html" title="Phloem and translocation">Phloem and translocation</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17722/meristems-and-growth.html" title="Meristems and Growth.">Meristems and Growth.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17804/hormonal-control-in-plants.html" title="Hormonal control in plants">Hormonal control in plants</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17725/reproduction-in-angiosperms.html" title="Reproduction in angiosperms.">Reproduction in angiosperms.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17808/seeds-flowering-phytochromes.html" title="Seeds, flowering & phytochromes">Seeds, flowering & phytochromes</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17888/hl-genetics-activities-for-learning.html" title="HL Genetics Activities for Learning">HL Genetics Activities for Learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17889/meiosis.html" title="Meiosis.">Meiosis.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17890/di-hybrid-crosses.html" title="Di-Hybrid Crosses.">Di-Hybrid Crosses.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17892/polygenic-inheritance.html" title="Polygenic Inheritance.">Polygenic Inheritance.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17891/gene-linkage-1.html" title="Gene Linkage 1">Gene Linkage 1</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17894/gene-linkage-2.html" title="Gene Linkage 2">Gene Linkage 2</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../17901/gene-pools.html" title="Gene pools">Gene pools</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19670/polyploidy.html" title="Polyploidy">Polyploidy</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../19559/hl-animal-physiology-activities-for-learning.html" title="HL Animal Physiology Activities for Learning">HL Animal Physiology Activities for Learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19560/antibody-production.html" title="Antibody production">Antibody production</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19566/monoclonal-antibodies.html" title="Monoclonal antibodies">Monoclonal antibodies</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19565/vaccination.html" title="Vaccination">Vaccination</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19561/muscles-joints.html" title="Muscles & joints">Muscles & joints</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19564/muscle-structure-function.html" title="Muscle structure & function.">Muscle structure & function.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19681/osmoregulation.html" title="Osmoregulation">Osmoregulation</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19562/kidney-and-nephrons.html" title="Kidney and nephrons.">Kidney and nephrons.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18813/gamete-formation.html" title="Gamete formation">Gamete formation</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../16365/fertilization-blastocyst.html" title="Fertilization & blastocyst">Fertilization & blastocyst</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20080/pregnancy-and-birth.html" title="Pregnancy and birth">Pregnancy and birth</a></li></ul></ul><li class=" parent std-toplevel" style="padding-left: 4px"><i class="expander fa fa-caret-right "></i><a class="" href="../17193/options-.html" title="Options ">Options </a></li><ul class="level-1 "><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../21490/option-a-neurobiology-activities-for-learning.html" title="Option A - Neurobiology - Activities for learning">Option A - Neurobiology - Activities for learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../21399/nervous-system-formation.html" title="Nervous system formation">Nervous system formation</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../21401/synapses-and-nervous-system-plasticity.html" title="Synapses and nervous system plasticity">Synapses and nervous system plasticity</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../21519/brain-structure-and-function.html" title="Brain structure and function">Brain structure and function</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../21520/the-cerebral-cortex.html" title="The Cerebral cortex">The Cerebral cortex</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../21525/sensory-receptors-and-smell.html" title="Sensory receptors and smell">Sensory receptors and smell</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../21526/the-eye-and-photoreceptors.html" title="The eye and photoreceptors">The eye and photoreceptors</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../33371/reflexes.html" title="Reflexes">Reflexes</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../33372/conditioning-and-imprinting.html" title="Conditioning and imprinting">Conditioning and imprinting</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../25280/option-b-biotechnology-and-bioinformatics.html" title="Option B - Biotechnology and bioinformatics">Option B - Biotechnology and bioinformatics</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../32571/batch-fermentation-and-continuous-culture.html" title="Batch fermentation and continuous culture">Batch fermentation and continuous culture</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../25411/cryptic-messages-bioinformatics-introduction.html" title="Cryptic messages - bioinformatics introduction">Cryptic messages - bioinformatics introduction</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../25364/orf-activity.html" title="ORF activity">ORF activity</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../22063/option-c-ecology-activities-for-learning.html" title="Option C - Ecology Activities for learning">Option C - Ecology Activities for learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22081/describing-communities.html" title="Describing communities">Describing communities</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22083/limits-and-zones-lab.html" title="Limits and zones lab">Limits and zones lab</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22084/symbiosis-v-competitive-exclusion.html" title="Symbiosis v Competitive exclusion">Symbiosis v Competitive exclusion</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22085/modelling-energy-flow.html" title="Modelling energy flow">Modelling energy flow</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22086/predicting-ecosystems.html" title="Predicting ecosystems">Predicting ecosystems</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22089/modelling-nutrients.html" title="Modelling nutrients">Modelling nutrients</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22088/disturbance-vs-diversity.html" title="Disturbance vs Diversity">Disturbance vs Diversity</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22807/invasive-species.html" title="Invasive species">Invasive species</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22810/biomagnification.html" title="Biomagnification">Biomagnification</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22958/plastic-debris.html" title="Plastic debris">Plastic debris</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../23153/indicator-species-biotic-index.html" title="Indicator species & biotic index">Indicator species & biotic index</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../23154/conservation-methods.html" title="Conservation methods">Conservation methods</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22059/biodiversity-estimations.html" title="Biodiversity estimations">Biodiversity estimations</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../22060/lincoln-index-activities.html" title="Lincoln Index activities">Lincoln Index activities</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../27387/population-growth-curves.html" title="Population growth curves">Population growth curves</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../27433/fisheries-and-populations.html" title="Fisheries and populations">Fisheries and populations</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18998/nitrogen-cycle-applications.html" title="Nitrogen cycle - applications">Nitrogen cycle - applications</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../28235/phosphorus-cycle.html" title="Phosphorus cycle">Phosphorus cycle</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../20088/option-d-human-physiology-activities-for-learning.html" title="Option D - Human physiology Activities for learning">Option D - Human physiology Activities for learning</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20215/is-it-so-bad-to-eat-only-pizza.html" title="Is it so bad to eat only pizza?">Is it so bad to eat only pizza?</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20220/appetite-and-malnutrition.html" title="Appetite and malnutrition">Appetite and malnutrition</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20284/exocrine-glands.html" title="Exocrine glands">Exocrine glands</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20300/control-of-digestive-secretions.html" title="Control of digestive secretions">Control of digestive secretions</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20259/a-miracle-cure-for-ulcers.html" title="A miracle cure for ulcers">A miracle cure for ulcers</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20664/liver-structure-function.html" title="Liver structure & function.">Liver structure & function.</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20665/jaundice-liver-function.html" title="Jaundice & liver function">Jaundice & liver function</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20692/cardiac-muscle-myogenic-control.html" title="Cardiac muscle & myogenic control">Cardiac muscle & myogenic control</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20707/cardiology-role-play.html" title="Cardiology Role play">Cardiology Role play</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../24113/epidemiology-framingham-heart-study.html" title="Epidemiology - Framingham heart study">Epidemiology - Framingham heart study</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20706/pituitary-gland-and-hormones.html" title="Pituitary gland and hormones">Pituitary gland and hormones</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20732/oxygen-dissociation-curves.html" title="Oxygen dissociation curves">Oxygen dissociation curves</a></li><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20708/carbon-dioxide-and-bohr-shift.html" title="Carbon dioxide and Bohr shift">Carbon dioxide and Bohr shift</a></li></ul></ul><li class=" parent std-toplevel" style="padding-left: 4px"><i class="expander fa fa-caret-right "></i><a class="" href="../17622/the-investigation.html" title="The Investigation">The Investigation</a></li><ul class="level-1 "><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../21187/individual-investigation-skills-introduction.html" title="Individual investigation - skills introduction">Individual investigation - skills introduction</a></li><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17179/practical-scheme-of-work.html" title="Practical Scheme of Work">Practical Scheme of Work</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../16860/lab-protocols-for-the-biology-ib-guide.html" title="Lab protocols for the Biology IB guide">Lab protocols for the Biology IB guide</a></li></ul><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17623/planning-for-skills-progression.html" title="Planning for skills progression">Planning for skills progression</a></li><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17624/personal-engagement.html" title="Personal Engagement">Personal Engagement</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19063/personal-engagement-personality-quiz.html" title="Personal Engagement - personality quiz">Personal Engagement - personality quiz</a></li></ul><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../34461/three-ways-to-choose-a-topic-for-the-ia.html" title="Three ways to choose a topic for the IA">Three ways to choose a topic for the IA</a></li><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17625/exploration.html" title="Exploration">Exploration</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../23429/focusing-a-research-question.html" title="Focusing a research question">Focusing a research question</a></li></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17626/analysis.html" title="Analysis">Analysis</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../26255/ia-analysis-anova-or-t-test.html" title="IA Analysis - ANOVA or t-test?">IA Analysis - ANOVA or t-test?</a></li></ul><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17627/evaluation.html" title="Evaluation">Evaluation</a></li><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17628/communication.html" title="Communication">Communication</a></li><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../38973/ia-ideas-during-a-pandemic-2020-21.html" title="IA ideas during a pandemic 2020-21">IA ideas during a pandemic 2020-21</a></li><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../30218/ia-avoiding-common-errors.html" title="IA - Avoiding common errors">IA - Avoiding common errors</a></li><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../34356/ia-experiments-that-could-be-done-at-home.html" title="IA Experiments that could be done at home">IA Experiments that could be done at home</a></li><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../34574/ia-experiment-ideas-inspired-by-youtube.html" title="IA experiment ideas inspired by Youtube">IA experiment ideas inspired by Youtube</a></li><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../15992/6-ecological-ideas-for-your-ia.html" title="6 Ecological ideas for your IA">6 Ecological ideas for your IA</a></li><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../20852/30-investigation-ideas-for-biology-ia.html" title="30 investigation ideas for Biology IA">30 investigation ideas for Biology IA</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../39689/investigating-strawberries-with-a-glucose-test-meter.html" title="Investigating strawberries with a glucose test meter">Investigating strawberries with a glucose test meter</a></li></ul><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../23240/16-new-experiment-ideas-for-biology-ia.html" title="16 new experiment ideas for Biology IA">16 new experiment ideas for Biology IA</a></li><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../26171/12-investigation-ideas-with-a-biological-twist.html" title="12 Investigation ideas with a biological twist.">12 Investigation ideas with a biological twist.</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../26186/body-temperature-data.html" title="Body temperature data">Body temperature data</a></li></ul><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../19329/ia-investigation-marking-sheet.html" title="IA Investigation - marking sheet">IA Investigation - marking sheet</a></li><li class="" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../21859/marking-rigour-ia-assessment-criteria.html" title="Marking rigour & IA assessment criteria.">Marking rigour & IA assessment criteria.</a></li></ul><li class=" parent std-toplevel" style="padding-left: 4px"><i class="expander fa fa-caret-right "></i><a class="" href="../18404/quizzes-tests-revision.html" title="Quizzes tests & revision">Quizzes tests & revision</a></li><ul class="level-1 "><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../17665/the-exams.html" title="The Exams">The Exams</a></li><ul class="level-2 "><li class="" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19051/describing-trends-in-ib-graphs.html" title="Describing trends in IB graphs">Describing trends in IB graphs</a></li><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20791/paper-3-section-a-questions.html" title="Paper 3 Section A - questions">Paper 3 Section A - questions</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../26073/graphical-analysis-skills-for-life.html" title="Graphical analysis - skills for life!">Graphical analysis - skills for life!</a></li></ul></ul><li class=" parent" style="padding-left: 14px"><i class="expander fa fa-caret-right "></i><a class="" href="../18403/a3-topic-revision-sheets.html" title="A3 topic revision sheets">A3 topic revision sheets</a></li><ul class="level-2 "><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18405/topic-1-cells-revision-activities.html" title="Topic 1 - Cells revision activities">Topic 1 - Cells revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../22372/topic-1-cells-sl-revision-list.html" title="Topic 1 - Cells SL revision list">Topic 1 - Cells SL revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19003/topic-2-molecular-biology-revision-activities.html" title="Topic 2 - Molecular biology revision activities">Topic 2 - Molecular biology revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../22373/topic-2-bio-molecules-sl-revision-list.html" title="Topic 2 - Bio molecules SL revision list">Topic 2 - Bio molecules SL revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../18999/topic-3-genetics-sl-revision-activities.html" title="Topic 3 - Genetics SL revision activities">Topic 3 - Genetics SL revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../22378/topic-3-genetics-sl-revision-list.html" title="Topic 3 - Genetics SL revision list">Topic 3 - Genetics SL revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19480/topic-4-ecology-sl-revision-activities.html" title="Topic 4 - Ecology SL revision activities">Topic 4 - Ecology SL revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../22395/topic-4-ecology-revision-list.html" title="Topic 4 - Ecology revision list">Topic 4 - Ecology revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19006/topic-5-evolution-sl-revision-activities.html" title="Topic 5 - Evolution SL revision activities">Topic 5 - Evolution SL revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../22474/topic-5-evolution-revision-list.html" title="Topic 5 - Evolution revision list">Topic 5 - Evolution revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20121/topic-6-human-physiology-sl-revision-activities.html" title="Topic 6 - human physiology SL revision activities">Topic 6 - human physiology SL revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../22396/topic-6-human-physiology-revision-list.html" title="Topic 6 - Human physiology revision list">Topic 6 - Human physiology revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20196/topic-7-nucleic-acids-hl-revision-activities.html" title="Topic 7 - Nucleic acids HL revision activities">Topic 7 - Nucleic acids HL revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../20139/topic-7-nucleic-acids-hl-revision-list.html" title="Topic 7 - Nucleic acids HL revision list">Topic 7 - Nucleic acids HL revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20787/topic-8-metabolism-hl-revision-activities.html" title="Topic 8 - Metabolism HL revision activities">Topic 8 - Metabolism HL revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../20198/topic-8-metabolism-hl-revision-list.html" title="Topic 8 - Metabolism HL revision list">Topic 8 - Metabolism HL revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20122/topic-9-plant-biology-hl-revision-activities.html" title="Topic 9 - Plant biology HL revision activities">Topic 9 - Plant biology HL revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../20773/topic-9-plants-hl-revision-list.html" title="Topic 9 - Plants HL - revision list">Topic 9 - Plants HL - revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../20849/topic-10-genetics-hl-revision-activities.html" title="Topic 10 - Genetics HL Revision activities">Topic 10 - Genetics HL Revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../20128/topic-10-genetics-hl-revision-list.html" title="Topic 10 - Genetics HL revision list">Topic 10 - Genetics HL revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="std-disabled" href="#" title="Topic 11 - Physiology HL Revision activities">Topic 11 - Physiology HL Revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../20115/topic-11-animal-physiology-revision-list.html" title="Topic 11 - Animal physiology revision list">Topic 11 - Animal physiology revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../23821/option-a-neurobiology-revision-activities.html" title="Option A - Neurobiology - Revision activities">Option A - Neurobiology - Revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../23822/option-a-neurobiology-sl-revision-list.html" title="Option A - Neurobiology SL Revision list">Option A - Neurobiology SL Revision list</a></li><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../23831/option-a-neurobiology-hl-revision-list.html" title="Option A - Neurobiology HL Revision list">Option A - Neurobiology HL Revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa fa-caret-right "></i><a class="" href="../19001/option-c-ecology-revision-activities.html" title="Option C - Ecology revision activities">Option C - Ecology revision activities</a></li><ul class="level-3 "><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../27865/option-c-ecology-sl-revision-list-.html" title="Option C - Ecology SL revision list ">Option C - Ecology SL revision list </a></li><li class="" style="padding-left: 42px"><i class="expander fa fa-caret-right "></i><a class="" href="../27863/option-c-ecology-hl-revision-list.html" title="Option C - Ecology HL revision list">Option C - Ecology HL revision list</a></li></ul><li class=" parent" style="padding-left: 28px"><i class="expander fa 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<div id="main-column" class="span9"> <article id="sa-to-volume-practical-activity" style="margin-top: 16px;">
<h1 class="section-title">SA to Volume practical activity</h1>
<ul class="breadcrumb"><li><a title="Home" href="../../../biology.html"><i class="fa fa-home"></i></a><span class="divider">/</span></li><li><span class="gray">SL Core </span><span class="divider">/</span></li><li><span class="gray">Cells: Activities for Learning </span><span class="divider">/</span></li><li><span class="active">SA to Volume practical activity</span></li></ul>
<div class="row-fluid">
<section class="span12" id="main-content">
<h2>What limits the maximum size of a cell?</h2>
<h3><img alt="" class="left" height="100" src="../../../ib/biology/images/agar%20blocks%20in%20acid%201-1.jpg" title="Acid indicator in agar blocks can show diffusion. Image credit: J McMurtry " width="133"></h3>
<p>The volume of a cell determines the needs of that cell for oxygen and other resources, as the metabolism increases according to the volume of cytoplasm.</p>
<p>The surface area controls the rate of uptake of the oxygen.</p>
<p>This experiment shows the effect of increasing size on the rate of diffusion of materials into and out of the cytoplasm of a cell.</p>
<hr class="hidden">
<div class="greyBg">
<h3>Lesson Description</h3>
<div class="blueBg">
<h4>Guiding Questions</h4>
<p>What is the effect of size on a living cell?</p>
<p>Does the surface area increase at the same rate as the volume in larger cells?</p>
</div>
<h4>Activity 1 Laboratory experiment</h4>
<p><a href="/media/ib/biology/files/SA%20to%20Vol%20student%20sheet.pdf" target="_blank" title="Worksheets"><img class="ico" src="../../../img/icons/exercise.png"> SA/Vol ratio- student instructions</a></p>
<p><iframe frameborder="0" height="260" scrolling="yes" src="/media/ib/biology/files/SA%20to%20Vol%20student%20sheet.pdf" width="100%"></iframe></p>
<div class="blueBg">
<h4>Safety</h4>
<p>Working with 1M acids - wear lab coats & eye protection.</p>
<p>The agar blocks contain alkali so wash hands afterwards.</p>
</div>
<h4>Method</h4>
<ol>
<li>Cut cubes of agar with the length of sides of 2.0 cm, 1.5 cm, 1.0 cm and 0.5 cm. <img alt="" class="right" height="177" src="../../../ib/biology/images/beaker_agarblocks.jpg" title="image: D Faure 2013" width="250"><br>
Several blocks of each size can be prepared.</li>
<li>Measurements should be as precise as possible and you should record the uncertainty of their measurements. This is often +/- the smallest unit on the ruler.</li>
<li>Pour enough 1M HCl into a beaker to just cover the largest block.</li>
<li>Place the agar blocks in the 1M HCl</li>
<li>Record the time taken for each of the blocks to change colour completely.<br>
Several blocks of each size can be placed in the same beaker.</li>
</ol>
<p>After the experiment:</p>
<p>The acid should be disposed of according to local rules, but typically pour into running water in the lab sinks.<br>
The agar can be disposed of in the garbage.</p>
<hr class="hidden">
<h4>Activity 2 Data processing</h4>
<ol>
<li>Make a table of the class data showing the times taken for colour change to occur in the blocks of different sizes.</li>
<li>Calculate averages and standard deviations</li>
<li>Present this processed data in an appropriate graph.</li>
<li>Write a Conclusion of the practical including an evaluation.</li>
</ol>
<h4></h4>
<h4>Theory: for use in the Conclusion</h4>
<section class="tib-hiddenbox">
<p>The simple geometry of cube volume Volume = l x w x h and surface area SA = 6*(l x h) is needed. Knowledge of how to use acids carefully and wearing eye protection is very important!</p>
<p><img alt="" class="right" height="183" src="../../../ib/biology/images/SA%20to%20Vol%20graph%281%29.jpg" title="Image credit: J McMurtry 23 Nov 2012" width="300"></p>
<div>
<p>Drawing unit cubes of 1 x 1 x 1 and 10 x 10 x 10 will get students to see the difference.</p>
<p>A big misconception students have is the unit size is the important factor and not the ratio of SA / Vol. Reducing the fractions to a ratio will help students to visualize this.</p>
<p>The crux of the matter is "why are cells so small?" so the emphasis is on keeping cells from getting too big. The graph of time taken for the colour change to occur versus the SA/Vol ratio is an inverse curve. The curve shows that as cells get larger, the ratio increases rapidly. As materials and heat move across the surface and are produced by the volume, a larger cell has trouble getting materials in fast enough to meet the metabolic needs while heat and wastes accumulate faster than the cell can lose these by diffusion. The consequence is for cells to do one of two things.</p>
<p style="margin-left: 40px;">1. cells divide to form smaller cells to increase the SA/Vol ratio</p>
<p style="margin-left: 40px;">2. increase their surface area by folding, as with the microvilli.</p>
<p style="margin-bottom: 1em;">Making the link as to why fingers, toes and ears get colder faster than other body parts can be useful to illustrate the SA/Volume ratio too. The ecological and evolutionary link of heat loss and ear size of Arctic foxes versus tropical desert foxes can also be made.</p>
</div>
</section>
<h4>Extension Activity</h4>
<p>Select images of structures, cells and organelles with scale bars to find the actual SA / Vol ratio. Here are images of red phagocytes with a 20.0 micron scale bar, bacterial cells with a 2 micron scale bar and microvilli with a 100nm scale bar.</p>
<p>Can students find the surface area to volume ratios of a cylinder such as microvilli and bacterial cells or for the sphere of phagocytes? Be sure to work in the same units as the agar blocks for comparisions!</p>
<section class="tib-hiddenbox">
<p><img alt="" class="left" height="300" src="../../../ib/biology/images/phagocyte%2020%20microns%20wikimedia%2022%20Nov%202012.jpg" title="Phagocytes. Image credit: GC Lugo, wikimedia 22 Nov 2012" width="271"><img alt="" class="right" height="196" src="../../../ib/biology/images/Helicobacter%20pylori.jpg" title="Helicobacter pylori. Image credit: CDC, wikimedia, 22 Nov 2012" width="300"></p>
</section>
<hr class="hidden">
<h4>Further reading</h4>
<p>In preparation for the stem cell topic, students should read about cell differentiation and specialisation.</p>
<div class="blueBg">
<h4>Questions to answer:</h4>
<ol>
<li>What is differentiation?</li>
<li>What is the difference between differentiation and specialization?</li>
<li>What are stem cells?</li>
<li>Where are stem cells found?</li>
<li>What can stem cells be used for?</li>
</ol>
</div>
<p style=""></p>
</div>
<div class="pinkBg">
<h3>Teachers notes</h3>
<h4>Preparation - 1 day in advance</h4>
<p>This practical takes less than 2 hours but the largest block (2.0 cm sides) can take over 20 minutes. The time remaining after the data collection can be used by the students to collect the class data for data processing. With the organisation and clean up time this could be done in one hour if everyone is well prepared.</p>
<p>The agar cake should be made no more than one day in advance as the agar is not sterilised and so will begin to support microbe growth. This growth can be reduced by refrigerating the agar and covering the surface tightly with cellowrap ( plastic food wrap).</p>
<h4>Materials</h4>
<p>A stiff agar cake can be made following this recipe. This needs to be tested with local materials so that the cake is quite stiff. If the agar is not stiff enough, the students will have trouble cutting neat blocks.</p>
<ul>
<li>Mix 180 g Agar-agar in 3dm<sup>3</sup> cool water and bring to a boil, stirring regularly. This will cause the agar-agar to dissolve.</li>
<li>Add 1 spatula Cresol red for the acid-base indicator, which turn purplish-red in alkali, pale yellow in acid.</li>
<li>Add 5 ml Sodium hydroxide 1M NaOH to obtain a purplish-red colour. Mix well for uniformity.</li>
<li>Pour into a cake pan or form ( not used for cakes anymore!) and allow to cool and solidify. This is best overnight.</li>
</ul>
<h4>Further Notes</h4>
<p>This process allows for the students to recognise the difficulty with an end point determination- when is the colour really gone. This is an important lesson for students to learn!</p>
<p>An alternative to this experiment is to make a stiff salt agar cake and to use datalogger conductivity probes to measure the changes of conductivity over time as the ions diffuse out of the agar. Different beakers would be needed for each cube.</p>
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