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Metabolism HL Paper 1 questions</a></label></li><li class=""><label style="padding-left: 0px"><i class="fa fa-fw"></i><a href="../2889/topic-9-plant-biology-hl-paper-1-questions.html">Topic 9 Plant biology HL Paper 1 questions</a></label></li><li class=""><label style="padding-left: 0px"><i class="fa fa-fw"></i><a href="../2890/topic-10-genetics-hl-paper-1-questions.html">Topic 10 Genetics HL Paper 1 questions</a></label></li><li class=""><label style="padding-left: 0px"><i class="fa fa-fw"></i><a href="../2891/topic-11-animal-physiology-hl-paper-1-questions.html">Topic 11 Animal physiology HL Paper 1 questions</a></label></li></ul></div> <div class="hidden-xs hidden-sm"> <button class="btn btn-default btn-block text-xs-center" data-toggle="modal" data-target="#modal-feedback" style="margin-bottom: 10px"><i class="fa fa-send"></i> Feedback</button> </div> </div> <div class="col-md-9" id="main-column"> <h1 class="page_title"> Topic 2 Molecular Biology Paper 1 questions <a href="#" class="mark-page-favorite pull-right" data-pid="2881" title="Mark as favorite" onclick="return false;"><i class="fa fa-star-o"></i></a> </h1> <ol class="breadcrumb"> <li><a href="../../../biology.html"><i class="fa fa-home"></i></a><i class="fa fa-fw fa-chevron-right divider"></i></li><li><a href="../2876/paper-1-style-exam-questions.html">Paper 1 style Exam questions</a><i class="fa fa-fw fa-chevron-right divider"></i></li><li><span class="gray">Topic 2 Molecular Biology Paper 1 questions</span></li> <span class="pull-right" style="color: #555" title="Suggested study time: 30 minutes"><i class="fa fa-clock-o"></i> 30'</span> </ol> <article id="main-article"> <h3><span class="mw-headline" id="Topic_1:_Cell_biology">Topic 2: <a class="internal-link" href="https://e.studyib.net/biology/page/463/02-molecular-biology">Molecular biology</a></span> <img alt="" src="../../images/02_molecules/dna_transcription_cc_flickr-1.jpg" style="float: right; width: 100px; height: 100px;"></h3> <p><span class="mw-headline">This page contains <strong>multiple choice questions</strong> in the style of Paper 1 of the Biology exams.<br> They test the breadth of your knowledge of the understandings and skills <strong>about molecular biology</strong>.</span><span class="mw-headline"><br> To spend more time reviewing the topic before answering these questions, use the revision resources.</span></p> <div class="index-list"> <div class="item"> <div class="bg-cover cover-96" onclick="window.location='/biology/page/463/02-molecular-biology'" style="background-image: url('../../images/02_molecules/simple_molecules_smaller-1.jpg')" title="02 Molecular biology"> </div> <div class="content"> <h4 class="head"><a href="../463/02-molecular-biology.html">Molecular biology revision resources</a></h4> <p class="body">This is an introduction to the molecular biology topic. It lists understandings and skills expected for Topic 2 including water, carbohydrates, lipids, proteins, enzymes, DNA, RNA, protein synthesis, respiration and photosynthesis. Detailed revision notes, activities and questions can be found on each of the sub-topic pages.</p> </div> </div> </div> <p><span class="mw-headline">Learn from any mistakes. Every question has an examiner's explanation that appears when you check your answers.<span class="mw-headline"><span class="mw-headline"><span class="mw-headline"><img alt="" src="../../images/00_random-images/check-button.png" style="width: 80px; height: 35px;"></span></span></span></span></p> <div class="tib-quiz dyn-quiz" data-pid="2881" data-mtime="1675505937.5125"><div class="label label-default q-number">1</div><div class="exercise shadow-bottom"><div class="q-question">What does the R-group on a diagram of an amino acid represent?</div><div class="q-answer"><p><label class="radio"><input type="radio"> A polar side chain.</label></p><p><label class="radio"><input type="radio"> The element Rubidium.</label></p><p><label class="radio"><input class="c" type="radio"> A molecular structure which is different in each amino acid.</label></p><p><label class="radio"><input type="radio"> An amphipathic region of the molecule.</label></p></div><div class="q-explanation"><p>There are about 20 different amino acids found in living organisms and each has a different molecular structure in the R-group.</p><p>This can be a simple -H atom, in alanine, or a more complicated structure.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">2</div><div class="exercise shadow-bottom"><div class="q-question"><p>What are the functions of the molecules cellulose and starch in plants?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Cellulose stores energy and starch is a component of cell walls.</label></p><p><label class="radio"><input type="radio"> Cellulose and starch are both important components of cell walls.</label></p><p><label class="radio"><input class="c" type="radio"> Cellulose is a component of cell walls and starch stores energy.</label></p><p><label class="radio"><input type="radio"> Cellulose is used for respiration and starch is stored in chloroplasts.</label></p></div><div class="q-explanation"><p>Plant cells walls are built mainly of cellulose.</p><p>Starch in the cell is found in the chloroplast and in the cytoplasm. It is used to store energy.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">3</div><div class="exercise shadow-bottom"><div class="q-question"><p>Which of the following molecules are monosaccharides?</p><ol><li>Lactose</li><li>Galactose</li><li>Sucrose</li><li>Fructose</li><li>Glucose</li></ol></div><div class="q-answer"><p><label class="radio"><input type="radio"> 1, 2 and 3 only</label></p><p><label class="radio"><input class="c" type="radio"> 2, 4 and 5 only</label></p><p><label class="radio"><input type="radio"> 2 and 3 only</label></p><p><label class="radio"><input type="radio"> 2 and 4 only</label></p></div><div class="q-explanation"><p>Monosacharides are Galactose, Fructose and Glucose.</p><p>The three disaccharides named in the syllabus are Maltose, Sucrose and Lactose.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">4</div><div class="exercise shadow-bottom"><div class="q-question"><p>Which enzymes are responsible for DNA replication?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> DNA replicase and helicase.</label></p><p><label class="radio"><input class="c" type="radio"> DNA polymerase and helicase.</label></p><p><label class="radio"><input type="radio"> DNA polymerase and DNA synthase.</label></p><p><label class="radio"><input type="radio"> RNA polymerase and DNA polymerase.</label></p></div><div class="q-explanation"><p>DNA polymerase builds a DNA polymer, and unwinds the DNA and separates the strands so that each can be used as a template.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">5</div><div class="exercise shadow-bottom"><div class="q-question"><p>It is important to know a few examples of proteins. One example is the light-sensitive pigment found in the rod cells of the eye. It is formed from two molecules, retinal and opsin. What is its name?</p></div><div class="q-answer"><p><label class="radio"> <input type="radio"> <span>Chlorophyll</span></label></p><p><label class="radio"> <input class="c" type="radio"> <span>Rhodopsin</span></label></p><p><label class="radio"> <input type="radio"> <span>Pheomelanin</span></label></p><p><label class="radio"> <input type="radio"> <span>Eumelanin</span></label> </p></div><div class="q-explanation"><p><b>Rhodopsin</b> is a light-sensitive pigment found in the rod cells of the eye that is formed from retinal and opsin (a protein)</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">6</div><div class="exercise shadow-bottom"><div class="q-question"><p>When bound to the active site, what effect do lactase enzymes have on the bonds holding glucose to galactose in the disaccharide lactose molecules?</p></div><div class="q-answer"><p><label class="radio"> <input type="radio"> <span>They are strengthened.</span></label> </p><p><label class="radio"> <input type="radio"> <span>They are broken.</span></label> </p><p><label class="radio"> <input type="radio"> <span>Nothing happens to them.</span></label> </p><p><label class="radio"> <input class="c" type="radio"> <span>They are weakened.</span></label> </p></div><div class="q-explanation"><p>They are weakened, making the hydrolysis reaction easier, lowering the activation energy of the reaction.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">7</div><div class="exercise shadow-bottom"><div class="q-question"><p>Which of the following best describes the role of molecular motion in enzyme catalysis?</p></div><div class="q-answer"><p><label class="radio"> <input class="c" type="radio"> <span>Reactions happen when substrate and enzyme molecules collide with one another</span></label> </p><p><label class="radio"> <input type="radio"> <span>Reactions happen when the active site and enzyme molecules collide with one another</span></label> </p><p><label class="radio"> <input type="radio"> <span>Collision happen when the active site and enzyme molecules react with one another</span></label> </p><p><label class="radio"> <input type="radio"> <span>Collision happen when substrate and protein molecules react with one another</span></label> </p></div><div class="q-explanation"><p>Reactions happen when substrate and enzyme molecules collide with one another.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">8</div><div class="exercise shadow-bottom"><div class="q-question"><p>Which term best describes the structure of DNA and RNA, both made from long chains of nucleotides?</p></div><div class="q-answer"><p><label class="radio"> <input type="radio"> <span>Polysaccharides</span></label> </p><p><label class="radio"> <input type="radio"> <span>Polypeptides</span></label> </p><p><label class="radio"> <input class="c" type="radio"> <span>Polymers</span></label> </p><p><label class="radio"> <input type="radio"> <span>Nucleotide chains</span></label> </p></div><div class="q-explanation"><p><strong>Polymers</strong> is the term that refers to DNA and RNA which are both made from long chains of nucleotides</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">9</div><div class="exercise shadow-bottom"><div class="q-question"><p>Which statement best describes DNA helicase?</p></div><div class="q-answer"><p><label class="radio"> <input type="radio"> <span>It is an enzyme which fills in the Okazaki fragments on a DNA strand after repliction</span></label> </p><p><label class="radio"> <input class="c" type="radio"> <span>It is an enzyme which separates and unwinds the two strands of a DNA double helix</span></label> </p><p><label class="radio"> <input type="radio"> <span>It is an enzyme which attaches the stand of RNA to the DNA</span></label> </p><p><label class="radio"> <input type="radio"> <span>It is an enzyme which catalyses the synthesis of a new DNA strand</span></label> </p></div><div class="q-explanation"><p>DNA helicases are enzymes which separate and unwind the two strands in a DNA double helix.<br>They disturb the hydrogen bonds between complementary bases.<br>They are able to move along the DNA molecule and they use ATP.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">10</div><div class="exercise shadow-bottom"><div class="q-question"><p>Why is the DNA code considered to be "universal"?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Because DNA is found in all organisms</label></p><p><label class="radio"><input class="c" type="radio"> Because all organisms use the same codons for the same amino acids</label></p><p><label class="radio"><input type="radio"> Because DNA is found throughout the universe</label></p><p><label class="radio"><input type="radio"> Because all organisms contain the same genes</label></p></div><div class="q-explanation"><strong>All organisms</strong> use the same DNA code. The codons for each amino acid are the same in all species. If a human insulin gene is put into bacteria it still codes for the same protein.</div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">11</div><div class="exercise shadow-bottom"><div class="q-question"><p>In which of the following does anaerobic respiration convert pyruvate in the cytoplasm into lactate?</p></div><div class="q-answer"><p><label class="radio"> <input type="radio"> B<span>acteria</span></label> </p><p><label class="radio"> <input type="radio"> <span> Fungi</span></label> </p><p><label class="radio"> <input type="radio"> M<span>itochondria</span></label> </p><p><label class="radio"> <input class="c" type="radio"> <span>Mammals</span></label> </p></div><div class="q-explanation"><p>The process of anaerobic respiration in <strong>muscle</strong>: converts pyruvate in the cytoplasm into lactate</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">12</div><div class="exercise shadow-bottom"><div class="q-question"><p>In which of the following metabolic processes is there a large yield of ATP?</p></div><div class="q-answer"><p><label class="radio"> <input type="radio"> <span>Anaerobic respiration (in cytoplasm)</span></label> </p><p><label class="radio"> <input type="radio"> <span>Phosphorylation (in stroma of mitochondria)</span></label> </p><p><label class="radio"> <input class="c" type="radio"> <span>Aerobic respiration (in mitochondria)</span></label> </p><p><label class="radio"> <input type="radio"> <span>Decarboxylation (in mitochondria)</span></label> </p></div><div class="q-explanation"><p>There a large yield of ATP in <strong>aerobic respiration</strong> (in the mitochondria)</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">13</div><div class="exercise shadow-bottom"><div class="q-question"><p>Which kind of bonds can form between water molecules?</p><p><img alt="" src="../../images/richard/water.jpg" style="width: 140px; height: 85px;"></p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Covalent</label></p><p><label class="radio"><input class="c" type="radio"> Hydrogen</label></p><p><label class="radio"><input type="radio"> Peptide</label></p><p><label class="radio"><input type="radio"> Ionic</label></p></div><div class="q-explanation"><p>Hydrogen bonds can form between the slightly positive hydrogen and slightly negative oxygen.</p></div><div class="remove-section" style="display: none;" title="Remove question field"> </div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">14</div><div class="exercise shadow-bottom"><div class="q-question"><p>Which of the following does <strong>not</strong> represent the formation of a polymer for energy storage?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Lipid synthesis</label></p><p><label class="radio"><input type="radio"> Synthesis of starch.</label></p><p><label class="radio"><input class="c" type="radio"> Synthesis of DNA.</label></p><p><label class="radio"><input type="radio"> Synthesis of glycogen.</label></p></div><div class="q-explanation"><p>Glycogen, lipids and starch are all energy-rich storage molecules, DNA is synthesised for cell reproduction.</p></div><div class="remove-section" style="display: none;" title="Remove question field"> </div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">15</div><div class="exercise shadow-bottom"><div class="q-question"><p>Which of the following is not a condensation reaction?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Synthesis of starch.</label></p><p><label class="radio"><input type="radio"> Synthesis of lipids.</label></p><p><label class="radio"><input class="c" type="radio"> Breakdown of a disaccharide.</label></p><p><label class="radio"><input type="radio"> Synthesis of glycogen.</label></p></div><div class="q-explanation"><p>Anabolic reactions are condensation reactions, monomers condensing to form polymers. Breakdown of dimers and polymers is catabolic hydrolysis.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">16</div><div class="exercise shadow-bottom"><div class="q-question"><p>The pH of human blood is maintained between 7.35 and 7.45, why is this important to the function of blood proteins?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Oxygen does not dissolve in acidic blood.</label></p><p><label class="radio"><input type="radio"> Low pH will destroy red blood cells.</label></p><p><label class="radio"><input class="c" type="radio"> If blood pH goes outside the normal range, blood proteins may function less efficiently.</label></p><p><label class="radio"><input type="radio"> High pH will damage capillaries.</label></p></div><div class="q-explanation"><p>Protein function can be affected by changes in pH even if it is a slight change that does not cause denaturation. The other answers are distractors, a slight change in pH will not destroy red blood cells or damage capillaries or affect oxygen solubility.</p></div><div class="remove-section" style="display: none;" title="Remove question field"> </div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">17</div><div class="exercise shadow-bottom"><div class="q-question"><p>Which is the best description of this molecule?</p><p><img alt="" src="../../images/richard/2.1-ribose.jpg" style="width: 180px; height: 134px;"></p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Starch</label></p><p><label class="radio"><input type="radio"> Glucose</label></p><p><label class="radio"><input class="c" type="radio"> Ribose</label></p><p><label class="radio"><input type="radio"> Disaccharide</label></p></div><div class="q-explanation"><p>The molecule has 5 carbon atoms so is Ribose (a pentose and a single molecule, monosaccharide).</p></div><div class="remove-section" style="display: none;" title="Remove question field"> </div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">18</div><div class="exercise shadow-bottom"><div class="q-question"><p>Cellulose and starch are both polymers of glucose. Why are they different in terms of their structure?</p><p><img alt="" src="../../images/richard/2.3-cellulose-starch.jpg" style="width: 199px; height: 308px;"></p></div><div class="q-answer"><p><label class="radio"><input type="radio"> They vary in their monomer unit.</label></p><p><label class="radio"><input type="radio"> They vary in the bonding of pentose molecules.</label></p><p><label class="radio"><input class="c" type="radio"> Starch is a polymer of α glucose molecules and cellulose is a polymer of β glucose molecules.</label></p><p><label class="radio"><input type="radio"> Cellulose is a polymer of α glucose molecules and starch is a polymer of β glucose molecules.</label></p></div><div class="q-explanation"><p>Polymers can vary in structure and function by different bonding of the monomers. These affect the shape of the polymer and its function.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">19</div><div class="exercise shadow-bottom"><div class="q-question"><p>Why is water needed for the process of photosynthesis to produce carbohydrate?</p></div><div class="q-answer"><p><label class="radio"><input type="radio"> To produce oxygen.</label></p><p><label class="radio"><input type="radio"> For photolysis.</label></p><p><label class="radio"><input class="c" type="radio"> As a source of hydrogen.</label></p><p><label class="radio"><input type="radio"> As a source of oxygen.</label></p></div><div class="q-explanation"><p>Hydrogen from water is combined in a series of reactions to eventually form carbohydrates.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="label label-default q-number">20</div><div class="exercise shadow-bottom"><div class="q-question"><p>The genetic code is shown in the illustration. If a point mutation occurs in DNA that changes GGG in the DNA molecule to CGG, what would change in the polypeptide structure produced by this mutation?</p><p><img alt="" src="../../images/2025-richard/d1.2-genetic-code.jpg" style="width: 195px; height: 180px;"></p></div><div class="q-answer"><p><label class="radio"><input type="radio"> Ala would be substituted by Phe.</label></p><p><label class="radio"><input type="radio"> No change in the polypeptide chain.</label></p><p><label class="radio"><input class="c" type="radio"> Phe would be substituted by Ala.</label></p><p><label class="radio"><input type="radio"> Gly would be substituted by Pro.</label></p></div><div class="q-explanation"><p>Point mutations occur in DNA, the genetic code altertion occurs in mRNA.</p></div><div class="actions"><span class="score" data-score="0"></span><button class="btn btn-default btn-sm btn-xs-block text-xs-center check"><i class="fa fa-check-square-o"></i> Check</button></div></div><div class="totals"><span class="score"></span><button class="btn btn-success btn-block text-center check-total"><i class="fa fa-check-square-o"></i> Check</button></div></div><hr> <p>Refresh this page to try a new set of 20 multiple choice questions. 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